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      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

      learn GT20029

      research compound made to degrade androgen receptors in scalp

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      community Long term minoxidil as a permanent solution

      in Minoxidil  27 upvotes 3 years ago
      A user is considering using minoxidil for hair loss and asks for advice on application and long-term effectiveness. Responses suggest minoxidil can be effective but may lose efficiency over time, and combining it with other treatments like finasteride might be more beneficial.

      community Kintor Pharmaceutical Announces AR-PROTAC (GT20029) Approved for Acne and Androgenic Alopecia Clinical Trials in China

      in Technology  14 upvotes 3 years ago
      The conversation discusses the approval of Kintor Pharmaceutical's AR-PROTAC (GT20029) for clinical trials in China for acne and androgenic alopecia. One user expresses optimism about new treatments being developed and seeks clarification on how the new drug works, specifically if it temporarily degrades the AR protein to reduce DHT sensitivity in hair follicles.

      community ghk-cu is potent 5-ar inhibitor?

      in Product  9 upvotes 11 months ago
      GHK-Cu is a potent inhibitor of the type 1 5-alpha reductase enzyme in hair follicles, which may reduce hair loss without the side effects associated with type 2 5-alpha reductase inhibitors. The user previously experienced side effects with 5-alpha reductase inhibitors and is considering GHK-Cu as an alternative.

      community What blood markers to get tested before starting any 5-AR inhibitor?

      in Treatment  4 upvotes 7 months ago
      The conversation is about which blood markers to test before starting a 5-AR inhibitor for hair loss. The user mentions already testing Total T, Free T, SHBG, Estradiol, Haematocrit, Red blood cell count, and White cell count, and asks if DHT or additional markers are needed.