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      Controlled Microtrauma Opens a Regenerative Window for Appendage-Bearing Skin Repair

      research Controlled microtrauma opens a regenerative window for appendage-bearing skin repair

      June 2026 in “bioRxiv (Cold Spring Harbor Laboratory)”
      This study tested a microneedle patch on rabbit and pig models to support skin regeneration, revealing that the treatment accelerated wound closure, reduced scar formation, and promoted hair-bearing tissue and follicle growth, suggesting a trauma-guided framework for skin restoration.
      Skin Wound Healing: Role of Bone Marrow Stem Cells in Regeneration

      research Skin Wound Healing

      5 citations , January 2016 in “Elsevier eBooks”
      This study found that combining AMD-3100 with FK506 in subimmunosuppressive doses enhanced stem cell release from bone marrow, resulting in 25% faster epithelialization in excisional wounds in rats and mice.

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