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    GlossaryAntiandrogen Therapy (Antiandrogen Drugs)

    reduces or blocks male hormones to treat certain conditions

    Antiandrogen Therapy, also known as androgen deprivation therapy (ADT), is a treatment that reduces the levels or blocks the effects of androgens (male hormones like testosterone) in the body. This therapy is commonly used to treat conditions like prostate cancer and androgenic alopecia (male pattern baldness) by slowing the growth of cancer cells or reducing hair loss, respectively.

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      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

      learn Bicalutamide

      a nonsteroidal anti-androgen, most commonly used orally for women

      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

      learn Fluridil

      a topical anti-androgen with less systemic involvement

    Research

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      Therapeutic Strategies for Treating Hair Loss

      research Therapeutic Strategies for Treating Hair Loss

      42 citations , March 2006 in “Drug Discovery Today: Therapeutic Strategies”
      The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
      Clinical Applications of Antiandrogens

      research Clinical Applications of Antiandrogens

      29 citations , October 1988 in “Journal of Steroid Biochemistry”
      Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.
      Antiandrogens and Androgen Inhibitors in Dermatologic Treatments

      research Antiandrogens and Androgen Inhibitors in Dermatologic Treatments

      November 2020 in “Elsevier eBooks”
      Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

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