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5 / 11 resultslearn Bicalutamide
a nonsteroidal anti-androgen, most commonly used orally for women
learn Pyrilutamide
highly targeted anti-androgen that might have minimal systemic effects
learn Cyproterone
a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor
learn Dutasteride
Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity
Research
5 / 1000+ results![Therapeutic strategies for treating hair loss](/images/research/611c433a-297d-4a22-a5d3-814008bb6add/small/12596.jpg)
research Therapeutic strategies for treating hair loss
The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
![Recent studies on the delivery of hydrophilic drugs in nanoparticulate systems](/images/research/a971e00f-f6a7-4deb-8b9a-edc150f8437f/small/18478.jpg)
research Recent studies on the delivery of hydrophilic drugs in nanoparticulate systems
Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.
![Testosterone Metabolism in Human Skin Cells in vitro and Its Interaction with Estradiol and Dutasteride](/images/research/7515b3d4-70e3-48c5-af9f-1b01489161df/small/28706.jpg)
research Testosterone Metabolism in Human Skin Cells in vitro and Its Interaction with Estradiol and Dutasteride
Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.
![Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition](/images/research/f55f411a-9859-45d1-ba63-d926be8584df/small/15260.jpg)
research Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition
The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
![Hydroxysteroid Dehydrogenase (17β -HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors:Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels](/images/research/31972a10-89f7-4504-99c9-7f07c4318a92/small/15176.jpg)
research Hydroxysteroid Dehydrogenase (17β -HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors:Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels
Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.
Community Join
5 / 599 resultscommunity RU-58841 Lung Disease Possibility | Chest pain, "heart issues", etc
Some users of RU-58841 report cardiovascular symptoms like heart palpitations and chest tightness, which may be linked to its metabolites causing lung disease. The safety of RU-58841 is uncertain due to lack of long-term data and concerns about product purity, especially from gray market sources.
community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp
Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.
community A topical antiandrogen is very necessary to add to the stack, finastride/Dutastride aren't enough to move the needle.
User added RU and pyrilutamide for hair growth and noticed more baby hairs. Others suggest sticking with fin and min, while some discuss the user's self-image and hair loss severity.
community Binding affinity of pyrilutamide!
Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.
community Why isn’t fluridil more widely used and known about?
Fluridil, an antiandrogen that is not widely used or known about due to its expense and lack of availability in the US. It is suggested as a potential alternative for people who don't want to lower their DHT through treatments such as Minoxidil, Finasteride, Nizoral shampoo, and Dermarolling.