3 citations
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June 2020 in “Open access rheumatology”
This case report reviews the management of Rowell syndrome in a patient initially diagnosed with Rhupus syndrome and highlights their development of erythema multiforme after certain medications.
November 2024 in “Rheumatology Advances in Practice”
This case report highlights a rare instance of visceral leishmaniasis presenting as seropositive rheumatoid arthritis in a patient with HIV, emphasizing the importance of considering chronic infections as a differential diagnosis in inflammatory arthritis, especially in diverse populations with a history of travel.
This case report documents a 44-year-old female with Down's syndrome who was diagnosed with both rheumatoid arthritis and gouty arthritis, highlighting her specific clinical presentation and treatment regimen.
In this case report, two patients with coexisting systemic lupus erythematous and neuromyelitis optica spectrum disorder achieved remission of SLE activity using an anti-CD19 monoclonal antibody.
30 citations
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October 2020 in “Nature Communications”
This study provides the first crystal structure of the human SRD5A2 enzyme, revealing key insights into its function and inhibition which may aid future drug development.
What makes cetirizine a unique anti-inflammatory option for your scalp?Laboratory work reports that cetirizine lowers PGD2 and other inflammatory mediators, which is why researchers have proposed it for the scalp. There is no approved topical product and the clinical evidence is one small unblinded pilot study in pattern hair loss, so scalp use is off-label and experimental.
Anti-hair loss shampoos, like the one with rosemary, quillaja, and jaborandi extracts, mainly support scalp health but are not effective for hair regrowth compared to treatments like finasteride or minoxidil. Ketoconazole 2% is noted as the only effective anti-hair loss shampoo, while others are often considered scams.
Anti-inflammatories like curcumin, quercetin, and vitamin E may help with hair loss when used alongside treatments like finasteride and dutasteride. Ketoconazole is also noted for reducing scalp inflammation and improving scalp health.
Switching from topical finasteride to oral Dutasteride and using Fluridil caused persistent testicular discomfort. The discomfort did not subside after stopping Fluridil, raising concerns about Dutasteride's role.
An 18-year-old experiencing hair loss and seborrheic dermatitis has tried finasteride, dutasteride, and various shampoos without success. They are considering anti-androgens like RU58841 and KX-826 for oil control and dandruff reduction.
Anti-androgens like Finasteride, Dutasteride, Metformin, and Topical Spironolactone cause hairline recession and increased cholesterol levels. The hairline recovers after stopping the drugs.