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research The potential of androgenic alopecia management from plant derivatives

1 citations , August 2020 in “Food Research”

This review discusses management strategies for androgenic alopecia using plant derivatives and highlights the need for prolonged efficacy but reports no new clinical findings.

Therapeutic Potential of Ishophloroglucin A from Ishige Okamurae in Androgenic Alopecia: Inhibition of 5α-Reductase Activity and Activation of the Wnt/β-Catenin Signaling Pathway in Human Dermal Papilla Cells

research Therapeutic potential of Ishophloroglucin a from Ishige okamurae in androgenic alopecia: inhibition of 5α-reductase activity and activation of the Wnt/β-catenin signaling pathway in human dermal papilla cells

January 2026 in “Applied Biological Chemistry”

This study found that Ishophloroglucin A from brown seaweed may treat androgenic alopecia by inhibiting 5α-reductase and promoting hair growth-related factors in human dermal papilla cells.

research Therapeutic Potentiality of Celtis choseniana Nakai on Androgenic Alopecia through Repression of Androgen Action and Modulation of Wnt/β-catenin Signaling

March 2023 in “Natural product sciences”

This study demonstrated that Celtis choseniana Nakai may help alleviate androgenic alopecia by enhancing hair regrowth and activating Wnt/β-catenin signaling in both a mouse model and cultured human cells.

research The Angiogenic Potential of Mesenchymal Stem Cells from the Hair Follicle Outer Root Sheath

8 citations , February 2021 in “Journal of Clinical Medicine”

This study found that mesenchymal stem cells sourced from hair follicle outer root sheath showed higher differentiation efficiency and angiogenic potential for vascular graft applications compared to adipose-derived stem cells.

research Potential targets in the discovery of new hair growth promoters for androgenic alopecia

59 citations , May 2014 in “Expert Opinion on Therapeutic Targets”

This review discusses current therapeutic targets and treatments for androgenic alopecia but reports no clinical results; the authors highlight the challenge of developing multi-target drugs for effective treatment.

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Community Join

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community IGFBP‐rP1 is a potential therapeutic target in androgenic alopecia

in Research/Science 13 upvotes 1 year ago

IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hair loss.

community How effective is topical spironolactone for androgenic alopecia?

in Female 1 upvotes 1 year ago

Topical spironolactone is discussed as a potential treatment for androgenic alopecia, with the user seeking feedback on its effectiveness. Minoxidil, finasteride, and other treatments like microneedling and keto shampoo are mentioned as alternatives.

community Melatonin emerging as new treatment for androgenic alopecia?

in Update 35 upvotes 1 year ago

Melatonin is being considered as a potential treatment for androgenic alopecia, with some users discussing its effects and combining it with other treatments like minoxidil and finasteride. Concerns about melatonin's impact on hormones and side effects from other treatments like ketoconazole were also discussed.

community Finasteride success for androgenic alopecia by a 27M physician (NO PICTURES)

4 upvotes 10 years ago

A 27-year-old male physician improved hair density using minoxidil 5% foam and finasteride 1mg every other day, with initial sexual side effects that subsided. He recommends trying finasteride for a year but warns against dutasteride due to potential liver effects.

community The mechanism of androgenic alopecia

36 upvotes 11 months ago

DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

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Learn

9 / 17 results

learn Ketoconazole

antifungal with some anti-androgenic benefits, often used as a shampoo

learn Minoxidil

An essential vasodilator with some anti-androgenic effects

learn Lavender

plant and natural oil with antimicrobial and some anti-androgenic effects

learn Azelaic Acid

acid used for antimicrobial, anti-inflammatory and anti-androgenic properties

learn Finasteride

Frontline, gold standard treatment for combatting androgenic alopecia

Does hair strand thickness decrease in men with androgenic alopecia? Can finasteride help restore it? Androgenic alopecia thins hair strands by miniaturizing follicles. The pivotal finasteride trials (1,553 men, 1 mg/day, two years) report increased hair counts and improved assessed appearance, but they measured density, not the diameter of individual strands, so the effect on thickness itself is not established.

learn Argan oil

Argan oil: Is it useful for androgenic alopecia, or just for making hair look nice? Argan oil primarily improves hair appearance but lacks proven effectiveness for androgenic alopecia.

learn Microneedling

Does microneedling help with all types of alopecia, or only androgenic alopecia? Microneedling is most effective for androgenic alopecia, with limited evidence for other types.

learn Verteporfin

Is Verteporfin effective for both androgenic alopecia and alopecia areata? Verteporfin is not effective for treating androgenic alopecia or alopecia areata.

learn Vitamin B5

Does Vitamin B5 prevent DHT-related androgenic alopecia? Vitamin B5 does not prevent DHT-related androgenic alopecia.

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