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      learn Bicalutamide

      a nonsteroidal anti-androgen, most commonly used orally for women
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      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia

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      a topical anti-androgen with less systemic involvement

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      community Methods Of Staying Safe On Ru58841 - My 2 Cents

      in Research/Science  9 upvotes 6 days ago
      RU58841 is used topically to prevent hair loss by blocking DHT, with suggestions to drink grapefruit juice, take breaks, avoid microneedling, and use lower concentrations to reduce side effects. Users discuss applying it at night to minimize systemic absorption.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  134 upvotes 8 months ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.