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    Research 10 of 1000+

    1. Intratumoral <i>De Novo</i> Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors Cancer research · 2011 · 402 citations
    2. Steroidogenesis inhibitors alter but do not eliminate androgen synthesis mechanisms during progression to castration-resistance in LNCaP prostate xenografts The Journal of Steroid Biochemistry and Molecular Biology · 2009 · 57 citations
    3. Design, synthesis and biological evaluation of novel 3-oxo-4-oxa-5α-androst-17β-amide derivatives as dual 5α-reductase inhibitors and androgen receptor antagonists Bioorganic & medicinal chemistry letters · 2017 · 3 citations
    4. Synthesis and in Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-oxo-4-androstene-17.beta.-carboxamides as 5.alpha.-Reductase Inhibitors and Antiandrogens Journal of Medicinal Chemistry · 1995 · 12 citations
    5. Synthesis and Study of Some 17a-aza-D-homo Steroids as 5α-Reductase Inhibitors Current Drug Discovery Technologies · 2020 · 1 citations
    6. Synthesis of mimics of steroid A ring as potential enzyme inhibitors Research Repository (Kingston University London) · 2002
    7. Synthesis and in vitro study of 17β-[N-ureylene-N,N′-disubstituted]-4-methyl-4-aza-5α-androstan-3-ones as selective inhibitors of type I 5α-reductase Bioorganic & Medicinal Chemistry · 1997 · 5 citations
    8. Natural Product-Inspired Bis(trifluoromethyl) Phenyl Hydroxycinnamate Derivatives as Promising Nonsteroidal Inhibitors of Human Steroid 5α-Reductase Type-1: Synthesis, <i>In Vitro</i>, and <i>In Silico</i> Studies ACS Omega · 2025
    9. Natural Product-InspiredBis(trifluoromethyl) PhenylHydroxycinnamate Derivatives as Promising Nonsteroidal Inhibitorsof Human Steroid 5α-Reductase Type-1: Synthesis, <i>InVitro</i>, and <i>In Silico</i> Studies OPAL (Open@LaTrobe) (La Trobe University) · 2025
    10. What does androgenetic alopecia have to do with COVID‐19? An insight into a potential new therapy Dermatologic Therapy · 2020 · 47 citations
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    Community 3 of 345

    1. DHT and 5AR respect post, it's importance within the brain Reddit · 3 Mar 2024
    2. MPB - Has anyone else seen this video on ABS-201? Reddit · 23 Sept 2026
    3. New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase Reddit · 22 May 2024
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    Learn 3 of 12

    1. Cyproterone a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor
    2. Finasteride Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically
    3. Clascoterone Topical androgen-receptor blocker, approved as an acne cream
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