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RU58841

also ru, PSK-3841, HMR-3841

Experimental topical anti-androgen sold as a research chemical

RU-58841, also known as PSK-3841 or HMR-3841, is a nonsteroidal antiandrogen (NSAA) which was initially developed in the 1980s by Roussel Uclaf, the French pharmaceutical company from which it received its name. It was formerly under investigation by ProStrakan for potential use as a topical treatment for androgen-dependent conditions including acne, pattern hair loss, and excessive hair growth. The compound is similar in structure to the NSAA RU-58642 but contains a different side-chain. These compounds are similar in chemical structure to nilutamide, which is related to flutamide, bicalutamide, and enzalutamide, all of which are NSAAs similarly. RU-58841 can be synthesized either by building the hydantoin moiety or by aryl coupling to 5,5-dimethylhydantoin.

Information, not medical advice. Talk to a licensed doctor or pharmacist before starting or changing a treatment.

Research 2

  1. Evaluation of RU58841 as an Anti-Androgen in Prostate PC3 Cells and a Topical Anti-Alopecia Agent in the Bald Scalp of Stumptailed MacaquesEndocrine · 1998 · 20 citations
  2. A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude miceBritish Journal of Dermatology · 1997 · 25 citations
All on OpenAlex →

Posts 20

  1. RU58841 3 Month Results while abusing PEDsReddit · 1 Jan 2026
  2. Safety of RU-58841: I talked to the Pharma Company that researched it, Human Clinical Trials, and Potential Reasons for DiscontinuationReddit · 12 Oct 2023
  3. What’s the consensus on RU58841 vs Pyrilutamide (Kx-826)?Reddit · 27 Mar 2026
  4. Any experiences with RU58841 5%?Reddit · 7 Jul 2021
  5. Where do YOU guys get trustworthy RU58841?Reddit · 2 Jun 2026
  6. Methods Of Staying Safe On Ru58841 - My 2 CentsReddit · 14 Jan 2025
  7. who in here has used ru58841 , and how did it goReddit · 2 Jan 2026
  8. CAUTION: My Experience with RU58841Reddit · 17 Sept 2023
  9. ¿La RU58841 vale la pena? ¿Alguien ha visto resultados con ella?Reddit · 3 Mar 2026
  10. Seriously concerning sides effects occurring on RU58841Reddit · 21 Dec 2020
  11. RU58841 5% is roughly equivalent to Dutasteride 2mg — here's whyReddit · 5 Mar 2026
  12. I spoke to the Guy who did the Ru58841 (PSK-3841) researchReddit · 19 May 2021
  13. RU58841 vs. KX-826 vs. CB-03-01Reddit · 30 May 2026
  14. Ru58841 questionReddit · 14 Apr 2017
  15. Important thing i discovered that makes ru58841 very effectiveReddit · 8 Feb 2026
  16. RU58841 users, do you have any side effects? If so, please explain.Reddit · 1 Dec 2020
  17. I'm losing it with RU58841 lol. Any fellow RU user help is appreciated.Reddit · 21 Jun 2026
  18. RU-58841 Lung Disease Possibility | Chest pain, "heart issues", etcReddit · 26 Feb 2024
  19. Should you take RU58841 for Hair Loss!? (Featuring Steve Cook)Reddit · 7 May 2026
  20. Ru58841 ruined my life. Here’s why.Reddit · 27 Mar 2022
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