38 citations
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June 2005 in “Acta Biochimica Polonica” The study demonstrated that the spleens of black C57BL/6 mice contained eumelanin, which differed in paramagnetic properties from the eumelanin found in hair shafts and anagen VI skin. The presence of splenic eumelanin was inconsistent, with some spleens completely lacking the pigment. The percentage of spotted spleens decreased with the progression of telogen after hair growth. The splenic eumelanin showed similarities to synthetic dopa melanin rather than skin or hair melanin, suggesting limited degradation compared to skin/hair pigment. It was hypothesized that splenic eumelanin might partially originate from skin melanin phagocyted by Langerhans cells or macrophages and transported to the spleen.
22 citations
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August 1999 in “Experimental Dermatology” Certain drugs can cause early hair growth in mice by affecting the nerves.
96 citations
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October 2000 in “The FASEB Journal” The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.
211 citations
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October 2001 in “The FASEB Journal” Noggin is necessary to start the hair growth phase in skin after birth.
84 citations
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July 2003 in “European journal of biochemistry” Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.