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research A Comparison of Methods of Anagen Synchronization in the Adult Rat Model of Chemotherapy-Induced Alopecia

January 2015 in “Journal of clinical and investigative dermatology”

This study found that clipping is the most effective method for anagen synchronization in adult rat models to mimic chemotherapy-induced alopecia, producing robust anagen phases without causing skin trauma.

research Splenic eumelanin differs from hair eumelanin in C57BL/6 mice.

38 citations , June 2005 in “Acta Biochimica Polonica”

This study found that spleens of black C57BL/6 mice contain eumelanin, with properties different from skin and hair melanin, and may originate from skin melanin transported by immune cells.

research Traumatic Alopecia in Trichotillomania: a Pathogenic Interpretation of Histologic Lesions in the Pilosebaceous Unit^*

37 citations , April 1977 in “Journal of Cutaneous Pathology”

This study found that specific histologic features in skin biopsies can help support a diagnosis of traumatic alopecia (trichotillomania), but not all markers are distinct to the condition.

research Angiogenin is expressed in human dermal papilla cells and stimulates hair growth

20 citations , October 2008 in “Archives of dermatological research”

This study found that angiogenin is expressed in human dermal papilla cells, where it might stimulate hair growth by promoting cell proliferation and local skin angiogenesis.

research Influence of Hair Growth Cycle on Lipid Composition of Mouse Epidermis and Dermis.

6 citations , November 1960 in “Experimental Biology and Medicine”

In this study, despite morphological differences in the hair growth cycle stages, the lipid composition of the epidermis and dermis showed no significant variation, though water content and cholesterol levels differed between these skin layers.

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community Now with the delay of GTA 6 to November 2026 and potentially another delay to 2027, we could actually be getting PP405 before GTA 6.

in Chat 177 upvotes 10 months ago

A potential baldness cure, possibly PP405, might be available before the release of GTA 6, which is delayed to 2026 or 2027. There is skepticism about the effectiveness and release timeline of PP405.

community Amplifica: Hope or Cope? A Review of Their Pipeline

9 upvotes 4 weeks ago

Amplifica's AMP-303 showed a modest increase in hair growth, but results were inconsistent and potentially misleading. Hyaluronic acid and osteopontin are being explored for hair growth, with varying effects on different hair types and conditions.

community PP405: Regrows Hair In 8 Weeks. Is This The Miracle Cure?

168 upvotes 7 months ago

PP405 is considered as a potential hair regrowth treatment, but users are skeptical due to past product failures. They compare it to Minoxidil and Finasteride, questioning its effectiveness and the intentions of pharmaceutical companies.

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