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research Morus alba Root Extract Induces the Anagen Phase in the Human Hair Follicle Dermal Papilla Cells

28 citations , July 2021 in “Pharmaceutics”

This study found that Morus alba root extract activates β-catenin in hair follicle dermal papilla cells, promoting the transition to the anagen phase and enhancing hair growth factor secretion.

research Abnormal inner root sheath of the hair follicle in the loose anagen hair syndrome: An ultrastructural study

31 citations , December 2010 in “Journal of the American Academy of Dermatology”

This study reports that structural abnormalities in the inner root sheath of hair follicles may cause the hair shaft to be loosely attached in patients with loose anagen hair syndrome.

research [An immunohistochemical study on cell differentiation in the outer root sheath of the normal human anagen hair follicles with antikeratin monoclonal antibodies].

6 citations , December 1990 in “PubMed”

This study examined the expression patterns of various cytokeratins in the outer root sheath of human anagen hair follicles, noting distinct differentiation patterns and localization of keratin markers.

research Effect of Minoxidil Sulfate on the Growth of Human Anagen Hair Follicles Grown in Collagen Gels, and on the Colony Growth of Human Cultured Outer Root Sheath Cells in vitro.

1 citations , January 1992 in “The Nishinihon Journal of Dermatology”

This study found that minoxidil sulfate did not enhance hair follicle growth or cell proliferation in isolated human hair follicles at concentrations of 0.1, 1, and 10 μg/ml.

Sanguisorba Officinalis Root Extract Has FGF-5 Inhibitory Activity and Reduces Hair Loss by Prolonging the Anagen Period

research Sanguisorba Officinalis Root Extract Has FGF-5 Inhibitory Activity and Reduces Hair Loss by Causing Prolongation of the Anagen Period

3 citations , January 2007 in “Nishinihon hifuka/Nishi Nihon hifuka”

This study found that Sanguisorba Officinalis Root Extract showed potential in reducing hair loss by inhibiting FGF-5 activity, extending hair growth phases in mice and reducing hair loss in human trials.

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community Losing hair without the white bulb, Tressless GPT's Response. Do you guys agree?

4 upvotes 1 year ago

Hair loss without a white bulb may indicate mechanical damage, anagen effluvium, alopecia areata, or traction alopecia. Seeking a specialist is recommended, but access can be difficult in smaller areas.

community Aminexil - is it possible that if you stop using it you lose more hair than you had originally?

1 upvotes 1 year ago

Aminexil is used to strengthen hair roots but stopping it may lead to hair thinning, unlike minoxidil which has more complex effects. The user did not use finasteride or minoxidil due to concerns about side effects.

community Sanguisorba Officinalis Root Extract, and other FGF-5 inhibitors?

4 upvotes 9 years ago

The conversation discusses the potential of Sanguisorba Officinalis Root Extract as a treatment for hair loss by inhibiting FGF-5. The user also mentions the product évolis, which is based on this extract but is only available in the US and Australia.

community Why is minoxidil the “regrowth stimulant” and finasteride “the maintenance”, when official studies show more growth on finasteride ?

in Research/Science 46 upvotes 6 months ago

Finasteride is more effective for long-term hair maintenance by addressing the root cause of hair loss, while minoxidil acts as a growth stimulant with faster visible results. Combining both treatments is optimal, with oral minoxidil often showing better results for some individuals.

community Why don't Minoxidil regenerated hairs become terminal on the head?

in Minoxidil 101 upvotes 1 year ago

Minoxidil helps hair growth by increasing blood flow and prolonging the growth phase, but it doesn't address the root cause of hair loss, such as DHT sensitivity. Finasteride can help maintain some gains by blocking DHT, but stopping Minoxidil often leads to hair loss because the new hairs are dependent on it.

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learn Dexpanthenol

precursor of vitamin B5 with hair stimulating effects

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Platelet-Rich Plasma

growth factors taken from your blood and injected into your scalp to stimulate hair

learn Overview

learn Beta Polypeptide

learn Caffeine

Does caffeine stimulate hair growth or only slow hair loss? Caffeine stimulates hair follicles in laboratory cultures, and one open-label trial in 210 men found a 0.2% caffeine topical non-inferior to minoxidil 5% on an anagen-ratio endpoint; there is no placebo-controlled evidence that it regrows hair, and none at all in alopecia areata or telogen effluvium.

learn Latanoprost

How does latanoprost work to make eyelashes and possibly scalp hair grow? Studies report that latanoprost, a prostaglandin analog, lengthens the anagen (growth) phase of hair follicles, which is the mechanism given for the eyelash thickening seen in glaucoma patients; on the scalp the evidence is one 16-man pilot study and animal work, so the effect there is unproven.

learn Adenosine

Adenosine: How natural is this ingredient and how does it act on the scalp? Adenosine is a naturally occurring compound that promotes hair growth by extending the anagen phase.

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