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research Characterization of human ovarian teratoma hair by using AFM, FT‐IR, and Raman spectroscopy

3 citations , April 2011 in “Microscopy research and technique”

This study found that hair from ovarian teratomas shares similar chemical composition and morphology with scalp hair, but differs in physical properties and cysteic acid bands.

research Metabolite screening of aromatic amine hair dyes usingin vitrohepatic models

16 citations , October 2009 in “Xenobiotica”

This study found no evidence that the tested hair dye ingredients undergo hepatic metabolism to reactive oxidized metabolites in human liver microsomes and hepatocytes.

research Design, synthesis and biological evaluation of novel 3-oxo-4-oxa-5α-androst-17β-amide derivatives as dual 5α-reductase inhibitors and androgen receptor antagonists

3 citations , May 2017 in “Bioorganic & medicinal chemistry letters”

This study identified compounds 11d and 11k as potential dual 5α-reductase inhibitors and AR antagonists with significant anti-proliferative effects on prostate cancer cell lines, suggesting they may offer therapeutic value.

research Regulation of Receptor Binding Specificity of FGF9 by an Autoinhibitory Homodimerization

24 citations , July 2017 in “Structure”

In this study, researchers found that ligand homodimerization controls the receptor binding specificity of the FGF9 subfamily, preventing off-target activation of FGFR "b" isoforms.

research Performance exploration of multi-gene panels of alopecia areata susceptibility and drug-binding targets

1 citations , March 2025 in “Frontiers in Physiology”

This study identified key genes linked to immune cells and potential therapeutic compounds for alopecia areata by evaluating upregulated genes from patient datasets, highlighting T and NK cell involvement in hair follicle attack and suggesting drug candidates through molecular docking and dynamics simulations.

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Community Join

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community Ultimate Stack without nuking your gender (you'll go broke)

86 upvotes 1 year ago

A hair loss treatment plan includes finasteride, dutasteride, RU58841, pyrilutamide, minoxidil, and microneedling to inhibit DHT and promote hair growth. It also recommends supplements like Reishi and Lion’s Mane mushrooms, and a shampoo with ketoconazole, caffeine, and melatonin.

community Finasteride alternative close to fda approval in the US

60 upvotes 4 months ago

Breezula, a topical treatment, is anticipated to be available in the US by mid-2027 as a potential alternative to finasteride with fewer systemic side effects. There is ongoing debate about its effectiveness and some users report similar side effects to finasteride.

community What else is good. Besides the big 3.

in Chat 35 upvotes 1 year ago

Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

community If DHT is the cause of hair loss why do so many still lose hair on dutasteride?

in Finasteride/Dutasteride 9 upvotes 4 weeks ago

Hair loss can persist despite using treatments like finasteride, dutasteride, and minoxidil due to factors like genetic sensitivity, incomplete DHT blockage, and other hormonal influences. Individual responses vary, and some may require a combination of treatments to stabilize hair loss.

community How likely do you think it is for PP405 to come out?

in Research/Science 21 upvotes 11 months ago

PP405 is a potential new hair loss treatment that works through metabolic pathways rather than hormonal ones, with an estimated market release between late 2027 and 2029. Current alternatives to finasteride include minoxidil, pyralutamide, fluridil, and RU58841, with hair transplants also being a viable option.

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Learn

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learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

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Clinics

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