research Intrinsic factors in the pathogenesis of hidradenitis suppurativa: Genetics, hormones, and the microbiome
Genetics, hormones, and microbiome changes contribute to hidradenitis suppurativa.
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5 / 1000+ resultsresearch P382 Scalp fungal microbiome and sebum composition in males with and without androgenetic alopecia
This study found that patients with androgenic alopecia exhibited higher levels of Malassezia colonization and altered sebum composition compared to individuals without AGA.
research The effects of caffeine and adenosine on the microbiome and lipidome of the scalp
In this study, researchers found that a shampoo containing caffeine and adenosine significantly altered the scalp microbiome and lipidome in subjects with hair loss over 12 weeks, which may suggest a role for these compounds in enhancing anti-hair loss processes.
research Dupilumab Alters Both the Bacterial and Fungal Skin Microbiomes of Patients with Atopic Dermatitis
This study found that administering dupilumab to patients with moderate-to-severe atopic dermatitis over 12 weeks altered both fungal and bacterial skin microbiomes, increasing microbial diversity and decreasing colonization by Malassezia and Staphylococcus aureus at lesion sites.
research Can antibiotic‐induced changes in the composition of the hair follicle microbiome regulate human hair growth?
This study shares preliminary findings that roxithromycin treatment tendentially increased hair shaft production and altered the hair follicle microbiota in human hair ex vivo, with substantial inter-individual differences observed.
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2 / 800 results- Can scalp micropigmentation be removed? SMP can be lightened or removed with laser, usually over several sessions and at considerable cost. Removal may be incomplete and can leave scars.
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2 / 1000+ resultscommunity Finasteride does deplete important nuero-active steroids
Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.
community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.
A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.
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