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HPLC Characterization, Molecular Docking, QSAR and Molecular Dynamics Simulation of Alstonia Boonei Phytochemical Analogs as Potent 5-Alpha Reductase Inhibitors

research HPLC characterization, molecular docking, QSAR and molecular dynamics simulation of Alstonia boonei phytochemical analogs as potent 5-alpha reductase inhibitors

2 citations , July 2025 in “Discover Chemistry.”

This study explored the optimization of phytochemicals from Alstonia boonei to develop potential 5-alpha reductase inhibitors for Benign Prostatic Hyperplasia, finding promising analogs with enhanced binding affinity and stability compared to Finasteride, warranting further experimental validation.

research Sport als Risikofaktor und therapeutisches Prinzip in der Dermatologie

18 citations , February 2002 in “Der Hautarzt”

This review discusses the dual effects of sporting activities on skin health, highlighting potential risks like skin diseases and benefits such as improved outcomes in chronic skin conditions, but reports no new clinical results.

Studies on the Antimicrobial Activity of Evolvulus Alsinoides, Murraya Koenigii, Lawsonia Inermis, Hibiscus Rosa-Sinensis, Azadirachta Indica Against Malassezia Furfur Using Fractional Factorial Design

research STUDIES ON THE ANTIMICROBIAL ACTIVITY OF EVOLVULUS ALSINOIDES, MURRAYA KOENIGII, LAWSONIA INERMIS, HIBISCUS ROSA-SINENSIS, AZADIRACHTA INDICA AGAINST MALASSEZIA FURFUR USING FRACTIONAL FACTORIAL DESIGN

1 citations , January 2016 in “International journal of research in ayurveda and pharmacy”

This study found that a herbal formulation optimized with specific concentrations of plant extracts showed promising antifungal activity against Malassezia furfur.

research Women Also Use 5α-Reductase Inhibitors—Reply

November 2017 in “JAMA internal medicine”

Women also use 5α-reductase inhibitors, and their effects differ from men.

research Women Also Use 5α-Reductase Inhibitors

November 2017 in “JAMA internal medicine”

This letter to the editor states that the titles of two recent pieces in JAMA Internal Medicine should have included "in Men.

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Community Join

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community Do none pharmaceutical treatments also work?

5 upvotes 3 months ago

Topical finasteride and Minoxidil are the most effective treatments for hair loss, with non-pharmaceutical options like PRP, stem cell therapy, and red light caps offering minimal additional benefits. Users suggest sticking to proven treatments unless cost is not a concern.

community Does your hair also look depressingly awful under fluorescent lights?

in Chat 39 upvotes 1 year ago

Fluorescent lighting makes hair look thinner, causing concern about appearance. Some users consider treatments like DUT, while others share experiences of hair looking better in different lighting or conditions.

community Min/Fin topical prescription also contains Latanoprost?

in Treatment 3 upvotes 1 year ago

A user discusses a topical prescription for hair regrowth containing Minoxidil, Finasteride, and Latanoprost, noting Latanoprost's side effect of promoting eyelash and eyebrow growth. Others share experiences and information about Latanoprost, highlighting its origins as a glaucoma drug and potential side effects.

community Could Minoxidil also be effective with Raynauds Syndrome

6 upvotes 1 year ago

The conversation discusses using oral Minoxidil, a vasodilator, for both Raynaud's Syndrome and hair loss. It also inquires about other hair loss treatments that improve blood flow.

community Finasteride Doubled my Total & Free Test but also my Estradiol - 8 months in

in Chat 32 upvotes 1 month ago

A 22-year-old male experienced increased testosterone and estradiol levels after 8 months on finasteride, leading to softer erections and reduced arousal. Suggestions included reducing finasteride dosage, using supplements like L-arginine, L-citrulline, zinc, and possibly tadalafil to improve symptoms.

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Learn

8 / 801 results

learn Melatonin

Does melatonin only prevent hair loss or also help it grow new hair? Melatonin may help prevent hair loss and stimulate new hair growth.

learn Hydrocortisone

When should hydrocortisone be used for hair loss — is it only for irritated scalps or also alopecia areata? Hydrocortisone is a low-potency topical steroid whose labelled use is calming scalp irritation such as dermatitis; for alopecia areata no verified human trial supports it on its own, and dermatologists generally use stronger prescription corticosteroids instead.

learn Estradiol

Does Estradiol only stop hair loss, or can it also help regrow hair? Estradiol can slow hair loss and may help regrow hair in some cases.

learn Hair Transplant

Is NeoGraft suitable for both men and women for hair transplants? NeoGraft is suitable for both men and women, but individual factors may affect its effectiveness.

learn Scalp Micropigmentation

Is scalp micropigmentation suitable for everyone? Scalp micropigmentation is not suitable for everyone; a consultation is essential.

learn Bimatoprost

a synthetic prostamide used to treat eyelashes also shows promise for stimulating hair growth on scalp

learn Tretinoin

the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil

learn Vitamin D

vitamin you should probably be taking for general health might also help your hair a little

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Experts

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Clinics

5 / 6 results