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Did you mean Congenital Alopecia?

Glossary Congenital Alopecia

condition where an individual is born without hair

Congenital Alopecia, also known as Congenital Hair Loss or Inherited Alopecia, is a condition where an individual is born without hair or with very sparse hair due to genetic factors. This type of alopecia is present at birth and can result from various genetic mutations that affect hair follicle development and function.

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Research

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research Atrichia congenita with papular lesions: A rare cause of pediatric alopecia

July 2025 in “TURKDERM”

In this study, the authors emphasize the importance of accurately diagnosing congenital atrichia with papules—a condition marked by hair loss and papular skin lesions—differentiating it from other similar disorders to prevent unnecessary treatments and inform families about its benign but irreversible nature.

research A rare cause of irrevocable childhood alopecia feigning alopecia universalis: Atrichia congenita with papular lesions

September 2022 in “IP Indian journal of clinical and experimental dermatology”

This case report describes an 8-year-old girl with atrichia congenita characterized by complete hair loss and papular lesions, attributed to an insertion mutation in the hairless gene.

research The rare association of congenital glaucoma, giant melanocytic nevus, alopecia, and hypospadias in an Egyptian child with neurofibromatosis type 1: a case report

September 2024 in “Egyptian Journal of Medical Human Genetics”

This case report adds to the understanding of neurofibromatosis type 1 by documenting an Egyptian child with the condition alongside multiple unusual congenital anomalies, highlighting the importance of considering NF1 when these features are present.

research PA31 Congenital alopecia areata: a systematic review

June 2023 in “British journal of dermatology/British journal of dermatology, Supplement”

This study suggests that congenital alopecia areata should be considered for newborns with alopecia, supporting the use of topical corticosteroids as a reasonable initial treatment option based on observed regrowth.

research Pachyonychia Congenita-Associated Alopecia. A Microscopic Analysis Using Transverse Section Technique

17 citations , April 1997 in “American Journal of Dermatopathology”

This report provides the first microscopic description of pachyonychia congenita-associated alopecia, identifying a combination of histological features that might be unique to this condition.

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Community Join

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community 31M. Just diagnosed with androgenic alopecia. Fears of min.

13 upvotes 1 year ago

A 31-year-old man with androgenic alopecia is considering treatments like finasteride, minoxidil, and ketoconazole shampoo but is worried about finasteride's side effects. Users recommend starting with finasteride or dutasteride for DHT blocking, suggesting topical solutions to reduce side effects.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community REVOLUTION in AUGUST: New possibilities according to Dr. Muñoz (pinacidil, cromakalim, diazoxide and nicorandil)

13 upvotes 1 year ago

Dr. Muñoz's discovery suggests that targeting potassium channels in fibroblasts could reactivate hair growth, offering new treatment possibilities for alopecia. Potential strategies include using minoxidil, diazoxide, and other potassium channel openers, as well as bioelectric devices and direct growth factor applications.

community Is this Better Than Topical Minoxidil? Topical Diazoxide

6 upvotes 1 year ago

Topical diazoxide may be a promising hair regrowth treatment, especially for those who don't respond to minoxidil, as it activates potassium channels without needing sulfation. It appears safe for topical use, avoiding systemic effects seen in oral use.

community Finasteride and Dutasteride results compilation thread

in Finasteride/Dutasteride 83 upvotes 1 year ago

Combining finasteride and dutasteride may enhance hair regrowth by targeting different enzymes, with positive results reported. Minoxidil, both oral and topical, is also used to improve effectiveness.

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Clinics

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Learn

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learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn GHK-Cu

Heard alopecia areata leaves scar-like spots? Some peptides are helping those areas regrow hair. Alopecia areata patches usually still have living follicles. Peptides are being studied as a possible add-on, but the evidence is small and early. See a dermatologist for treatment.

learn Salicylic acid

What makes alopecia areata different from other types of hair loss, and can topical Salicylic acid treatments help regrow the affected areas? Alopecia areata is an autoimmune condition, and salicylic acid does not promote hair regrowth.

learn Finasteride

Does hair strand thickness decrease in men with androgenic alopecia? Can finasteride help restore it? Androgenic alopecia thins hair strands by miniaturizing follicles. The pivotal finasteride trials (1,553 men, 1 mg/day, two years) report increased hair counts and improved assessed appearance, but they measured density, not the diameter of individual strands, so the effect on thickness itself is not established.
Finasteride for alopecia: the definitive guide to using it correctly. Finasteride 1 mg daily blocks DHT and, in trials, slowed hair loss in most men over 6 to 12 months, though some men do not respond and the benefit lasts only while the drug is taken. It is prescription-only and carries a pregnancy contraindication.

learn TDM-105795

What types of alopecia or hair loss conditions might TDM-105795 be designed to target based on current research? TDM-105795 may target non-scarring alopecia, particularly androgenetic alopecia.

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