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GlossaryAllografts

tissue transplants between genetically different members of the same species

Allografts, also known as allogeneic grafts, refer to tissue transplants between genetically non-identical members of the same species. This type of graft is commonly used in medical procedures such as organ transplants, skin grafts, and bone marrow transplants. While allografts can be life-saving, they often require immunosuppressive drugs to prevent the recipient's immune system from rejecting the foreign tissue.

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research UVB-Induced Depletion of Donor-Derived Dendritic Cells Prevents Allograft Rejection of Immune-Privileged Hair Follicles in Humanized Mice

6 citations , November 2018 in “American journal of transplantation”

UV light helped human hair transplants survive in mice without broad immunosuppression.

research Contribution of Androgens to Chronic Allograft Nephropathy Is Mediated by Dihydrotestosterone

25 citations , November 2001 in “Kidney International”

Male hormones worsen kidney transplant damage, but blocking them helps.

research Long-Term Survival of Skin Allografts in Rats Treated with Topical Cyclosporine

22 citations , July 1987 in “Transplantation”

Topical cyclosporine significantly extends skin graft survival in rats.

research Amniotic Allograft Implantation for Midface Aging Correction: A Retrospective Comparative Study with Platelet-Rich Plasma

10 citations , June 2019 in “Aesthetic Plastic Surgery”

Amniotic allograft may be more effective than platelet-rich plasma for midface aging treatment.

research Umbilical Remnant Allograft Application in the Treatment of Erosive Pustular Dermatosis of the Scalp

2 citations , May 2022 in “JAAD case reports”

Using powdered umbilical remnant allograft can effectively treat chronic scalp wounds resistant to traditional treatments.

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community Expectations control for SCUBE3

in Research/Science 22 upvotes 1 year ago

SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.