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GlossaryAllografts

tissue transplants between genetically different members of the same species

Allografts, also known as allogeneic grafts, refer to tissue transplants between genetically non-identical members of the same species. This type of graft is commonly used in medical procedures such as organ transplants, skin grafts, and bone marrow transplants. While allografts can be life-saving, they often require immunosuppressive drugs to prevent the recipient's immune system from rejecting the foreign tissue.

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research A New Horizon in Facial Plastic Surgery: Skin Tissue Engineering and Stem Cell Therapy—Reality or Dream?

2 citations , September 2014 in “The American Journal of Cosmetic Surgery”

Stem cells could potentially rebuild missing structures in wounds, improving facial skin replacement techniques.

research UVB-Induced Depletion of Donor-Derived Dendritic Cells Prevents Allograft Rejection of Immune-Privileged Hair Follicles in Humanized Mice

6 citations , November 2018 in “American journal of transplantation”

UV light helped human hair transplants survive in mice without broad immunosuppression.

research Lineage Commitment of Dermal Fibroblast Progenitors Is Mediated by Chromatin De-repression

1 citations , March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.

research Advanced Therapies for Skin Injuries

28 citations , September 2015 in “Wiener Klinische Wochenschrift”

New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.

research Bioengineering Skin Constructs

1 citations , November 2014 in “Elsevier eBooks”

Future research should focus on making bioengineered skin that completely restores all skin functions.

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community Expectations control for SCUBE3

in Research/Science 21 upvotes 2 years ago

SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

community Exosomes - do they work as results look promising?

in Treatment 2 upvotes 5 years ago

Exosomes are being considered for hair regrowth, with some users reporting initial improvement. One user moved on to using dutasteride and oral minoxidil with positive results.

community Occipitalis Muscle Tension Theory

in Treatment 7 upvotes 1 month ago

Scalp tension from the occipitalis muscle is theorized to contribute to hair loss, but most believe DHT and genetics are the main causes. Treatments like finasteride and minoxidil are considered more effective than addressing scalp tension.