May 2017 in “Journal of The American Academy of Dermatology” This study found an increase in allergic contact dermatitis cases linked to natural products like propolis and marigold, predominantly affecting women in a Bulgarian population.
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November 2002 in “Contact Dermatitis” This study found that adverse reactions to para-phenylenediamine in hair dye, including severe allergic contact dermatitis, may be more common than currently reported and often misdiagnosed.
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April 1991 in “Journal of The American Academy of Dermatology” Minoxidil solution can cause skin irritation and allergies in some users.
July 2026 in “International Journal of Applied Pharmaceutics” This review discusses the dermatological and systemic adverse effects of hair dye use, particularly focusing on the common allergen para-phenylenediamine, and reports no new clinical data.
January 2025 in “Ciência Rural” This case study reports a cutaneous adverse drug reaction in a dog caused by prolonged topical exposure to benzyl benzoate, leading to irritant contact dermatitis, but healing occurred within three weeks after changing treatment.