Cutaneous Adverse Drug Reaction Associated With Topical Use of Benzyl Benzoate in a Dog

    January 2025 in “ Ciência Rural ”
    Fabiana Wurster Strey, Marinara Macelai Leite, Julmar Paul Ascensios Vargas, Bruno Leite Anjos
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    TLDR Improper use of benzyl benzoate on a dog can cause severe skin reactions.
    This paper presents a case of cutaneous adverse drug reaction (CADR) in a 2-year-old Pit Bull due to the improper use of benzyl benzoate (BB), resulting in irritant contact dermatitis (ICD) with symptoms like ulcerative skin lesions, hair loss, and itching. A biopsy confirmed CADR, and treatment involved stopping BB use and applying a topical ointment, leading to significant improvement within 48 hours and complete healing in 3 weeks. The study emphasizes the risk of prolonged BB exposure in dogs, noting that ICD can mimic allergic contact dermatitis (ACD), complicating diagnosis.
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