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    Glossary Alkylating Agents

    chemotherapy drugs that damage DNA to kill cancer cells

    Alkylating agents are a type of chemotherapy drug that work by adding an alkyl group to the DNA of cancer cells, which interferes with their ability to replicate and ultimately leads to cell death. These agents are used to treat various types of cancer, but they can also affect normal cells, leading to side effects such as hair loss (alopecia).

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      research Alkylating Agents

      November 2013
      This article reviews the history and dermatologic side effects of alkylating agents used in chemotherapy, noting that some agents like chlorambucil can cause recurrent symptoms upon rechallenge, whereas others are tolerated.
      Cancer Treatments and Alopecia: A Systematic Review

      research Cancer Treatments and Alopecia: A Systematic Review

      2 citations , January 2021 in “Turkiye Klinikleri Journal of Internal Medicine”
      This study outlines the temporary or sometimes permanent hair loss caused by cancer treatments, noting it often starts 2-3 weeks after chemotherapy and highlights the need for more research into prevention and treatment strategies for therapy-related alopecia.