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This review examines recent research on optimizing the structures of steroidal inhibitors for key steroidogenic enzymes used as cancer treatments, reporting on 209 new compounds with preclinical data that suggest structural modifications hold promise for developing new antineoplastic agents.

Some drugs can cause hair loss or increase hair growth, but these effects are usually reversible when the drug is stopped.

Some drugs can cause hair loss, and stopping these drugs often leads to hair regrowth.

This study elucidates a mechanism for acne-like skin toxicity caused by EGFR/MEK inhibitors, involving an interaction with skin bacteria to trigger inflammation, which supports existing antibiotic treatment practices.

This case report highlights the rare occurrence of life-threatening aplastic anemia in a 65-year-old woman treated with temozolomide for glioblastoma multiforme, emphasizing the need for more frequent blood monitoring to detect severe bone marrow suppression early.