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research Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition

295 citations , September 2006 in “Cell Cycle”

This review discusses the role of the TOR pathway in aging and suggests that rapamycin could potentially target age-related diseases, but reports no new clinical results.

research Timing of expression of the core clock gene Bmal1 influences its effects on aging and survival

237 citations , February 2016 in “Science Translational Medicine”

This study found that many effects previously thought to be caused by circadian rhythm disruption in Bmal1 knockout mice are actually due to BMAL1's properties unrelated to its clock function.

research Hair cycle and hair pigmentation: dynamic interactions and changes associated with aging

152 citations , December 2003 in “Micron”

This review discusses the development, regulation, and aging of the human hair follicle pigmentary system and suggests potential for reversing hair graying by manipulating follicle melanocytes in vitro, but reports no clinical results.

research Human skin stem cells and the ageing process

143 citations , September 2008 in “Experimental gerontology”

This review discusses the diverse roles and characteristics of epidermal and dermal stem cells in skin regeneration and aging, highlighting their potential applications in regenerative medicine and reports no new clinical results.

research From causes of aging to death from COVID-19

122 citations , June 2020 in “Aging”

This review discusses the hyperfunction theory of aging as a key factor in COVID-19 vulnerability, highlighting the potential of anti-aging interventions like rapamycin to reduce this risk.

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Learn

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learn Argine

learn Arginine

learn Dihydroxypropyl Arginine Hydrochloride

learn L- Arginine HCL

learn L- Arginine Alpha- Ketoglutarate

learn Biotin

Biotinyl-GHK: a miracle ingredient against hair loss? Biotinyl-GHK (biotinoyl tripeptide-1) is a cosmetic ingredient, not an approved hair-loss medicine; the published studies test it only inside multi-ingredient complexes such as Procapil, so no result can be attributed to the peptide itself.

learn Saw Palmetto

Is saw palmetto as effective as finasteride against DHT? In the only head-to-head hair study, which was open-label, fewer men improved on saw palmetto (38%) than on finasteride (68%). That study did not measure DHT levels.

learn Hair Transplant

When can I wear makeup again after a hair transplant? Wait 7 to 14 days after a hair transplant before wearing makeup.

learn Clascoterone

What is clascoterone and how does it work against hair loss? Clascoterone blocks androgen receptors in the skin. It is approved only for acne; a scalp solution is still investigational for hair loss.

learn KY19382

How does KY19382 actually stimulate dormant hair follicles to grow again? In mouse and cell studies, KY19382 reactivated hair follicles via Wnt/β-catenin signalling; it has never been tested in humans.

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Community Join

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community Thinning again after solid results

in Finasteride/Dutasteride 4 upvotes 2 months ago

A 28-year-old using 1mg Finasteride and 2.5mg Minoxidil since September 2024 noticed hair shedding after initial success and is considering switching to Dutasteride. Users suggest it might be a temporary shed, recommend checking for deficiencies, and advise against an immediate switch, suggesting consistency and possibly increasing Minoxidil dosage.

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