6 citations
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April 2018 in “Transplantation proceedings” This case report describes severe agranulocytosis and alopecia in a Japanese woman after starting azathioprine, highlighting the potential role of NUDT15 genetic screening in preventing adverse reactions to the drug.
55 citations
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December 1983 in “Acta Neurologica Scandinavica” This review discusses the side effects of carbamazepine, valproate, and clonazepam, noting that these are rare with long-term use but more common, transient, and generally mild during early treatment.
1 citations
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April 2017 in “European Psychiatry” This case study describes a patient who developed mild eosinophilia and a skin rash after starting clozapine, which resolved without discontinuing the medication.
July 2026 in “Anales de la Facultad de Ciencias Médicas (Asunción)” In this case report, azathioprine was linked to anagen effluvium in a 36-year-old woman after two weeks of use; hair regrowth occurred once the drug was stopped and minoxidil treatment was started.
April 2018 in “Journal of Investigative Dermatology” In this study, researchers found that the NUDT15 R139C gene variant is a significant genetic risk factor for azathioprine-induced severe myelotoxicity in Japanese patients with dermatological conditions, suggesting that screening for this variant may help prevent adverse reactions in East-Asian populations.