This study found that the age of onset in systemic lupus erythematosus patients affects clinical features, with juvenile-onset SLE showing more severe disease activity and systemic involvement than adult or late-onset SLE.
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January 2015 in “Pediatric Rheumatology” This review highlights the importance of recognizing mucocutaneous lesions in diagnosing juvenile-onset systemic lupus erythematosus, noting that these lesions often improve with controlled lupus and can indicate disease activity.
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April 2016 in “Journal of Reproductive Health and Medicine” This article reviews challenges in diagnosing new-onset SLE during pregnancy, emphasizing the complexity of distinguishing it from normal pregnancy changes and preeclampsia, and reports no new results.
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December 2023 in “Mediterranean Journal of Rheumatology” This study reports that late onset systemic lupus erythematosus in India shows distinct clinical and serological characteristics compared to young onset cases, particularly in symptoms such as interstitial lung disease and autoantibody profiles.
May 2025 in “The Journal of Rheumatology” This report describes two cases where female patients with chronic granulomatous disease developed manifestations of systemic lupus erythematosus, highlighting a rare association that may influence clinical evaluation and treatment planning.
