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research An antimicrobial microneedle patch promotes functional healing of infected wounds through controlled release of adipose tissue-derived apoptotic vesicles

10 citations , September 2024 in “Journal of Nanobiotechnology”

This study developed an antimicrobial microneedle patch for delivering apoptotic vesicles to treat infected wounds, which was found to effectively reduce bacterial growth and accelerate scarless healing, including the rapid formation of mature hair follicles in just 8 days, a previously unreported early outcome.

research Generation of functionally active resident macrophages from adipose tissue by 3D cultures

2 citations , June 2024 in “Frontiers in Immunology”

In this study, researchers developed a 3D in-vitro system for generating functional AT-resident macrophages without cell sorting, providing a valuable tool to study their differentiation and function in various physiological and pathological conditions.

research Composition, isolation, identification and function of adipose tissue-derived exosomes

63 citations , January 2021 in “Adipocyte”

This review discusses the physiological and pathological roles of adipose tissue-derived exosomes and highlights areas for future research, without presenting new experimental findings.

research Evidence for Masculinization of Adipokine Gene Expression in Visceral and Subcutaneous Adipose Tissue of Obese Women With Polycystic Ovary Syndrome (PCOS)

58 citations , January 2013 in “The Journal of Clinical Endocrinology and Metabolism”

This study suggests that sexual dimorphism in adipose tissue functions may be linked to androgen levels, as women with PCOS demonstrated a more masculine adipokine expression pattern.

research Adipose tissue remodeling via TSLP-mediated IL-4/IL-13 signaling: Implications for atopic dermatitis and skin barrier

June 2024 in “Journal of Allergy and Clinical Immunology”

In this study, thymic stromal lymphopoietin (TSLP) induced IL-4/IL-13 from T cells, prompting sebum secretion and adipose loss, suggesting IL-4/IL-13 may affect skin barrier function in atopic dermatitis.

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Community Join

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community Increased adipose tissue (being overweight) in males may increase likelyhood of finasterde side effects

in Research/Science 29 upvotes 2 years ago

Being overweight may increase finasteride side effects due to higher aromatase activity converting testosterone to estradiol. Maintaining a healthy weight could reduce these side effects.

community If PP405 goes systemic this would be quite catastrophic

in Research/Science 4 upvotes 1 year ago

Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.

community Why does finasteride increase sexual desire in some users while significantly reducing it in others?

27 upvotes 3 weeks ago

Finasteride affects libido differently in individuals due to hormonal changes, increasing testosterone and potentially estrogen, which can either boost or reduce sexual desire. Other treatments mentioned include dutasteride and topical applications, with some users experiencing increased libido and others experiencing a decrease.

community What can be the real reason of Finasteride SE ?

18 upvotes 1 year ago

Finasteride can cause side effects like erectile dysfunction and decreased libido, possibly due to increased estradiol from testosterone aromatization, especially in those with higher body fat. Side effects vary widely and may also be influenced by genetic factors or neurosteroid inhibition.

community My derm said they came up with a new serum that is better then fin? What’s y’all’s thoughts

8 months ago

A new serum claims to enhance hair regrowth by amplifying oxygen delivery, improving the effectiveness of treatments like exosomes and peptides. Users are skeptical, questioning its efficacy compared to established treatments like Minoxidil and Finasteride.

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