This study suggests that the EULAR/ACR classification criteria for SLE may help predict organ damage, particularly in renal, cardiovascular, dermatological, and gonadal domains.
109 citations
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November 2004 in “Lupus” This article reviews the current ACR classification criteria for systemic lupus erythematosus, highlighting their dermatologic limitations, and proposes guidelines for a study to update these criteria.
39 citations
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September 2017 in “The Open Rheumatology Journal” This review discusses the role of complement activation in SLE and suggests that while monitoring C3 and C4 remains important, increased levels of cell-bound complement activation products may better indicate disease activity.
December 2025 in “Cureus” This case report highlights the importance of considering SLE in young male patients with unexplained inflammatory musculoskeletal symptoms, as systemic inflammation was identified and symptoms improved with hydroxychloroquine.
In this case report, a patient's atypical neuropsychiatric and dermatological symptoms were crucial for diagnosing systemic lupus erythematosus, highlighting the disease's clinical heterogeneity and the importance of early detection to prevent organ damage.