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GlossaryAdaptive Immunity (Acquired Immunity)

system learns to recognize and remember specific pathogens

Adaptive immunity, also known as acquired immunity or specific immunity, is the part of the immune system that learns to recognize and remember specific pathogens. Unlike innate immunity, which provides a general defense, adaptive immunity tailors its response to each unique invader, improving its effectiveness over time. This system involves specialized cells like T cells and B cells, which can remember past infections and provide a faster, more robust response upon subsequent exposures.

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research Genes and Immune Response in Alopecia Areata: Review of the Alopecia Areata Research Summit First Day Proceedings

6 citations, December 2013 in “Journal of Investigative Dermatology Symposium Proceedings”

Alopecia areata involves complex immune and genetic factors, with potential treatment targets identified, but more research is needed.

research Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity

717 citations, June 2010 in “Nature”

Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.

research Group IID, IIE, IIF, and III Secreted Phospholipase A2s

23 citations, August 2018 in “Biochimica and biophysica acta. Molecular and cell biology of lipids”

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Immunological Aspects and Gender Bias During Respiratory Viral Infections Including Novel Coronavirus Disease-19 (COVID-19): A Scoping Review

research Immunological Aspects and Gender Bias During Respiratory Viral Infections Including Novel Coronavirus Disease-19 (COVID-19): A Scoping Review

11 citations, May 2021 in “Journal of Medical Virology”

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

research Toll-Like Receptor 4 (TLR4): New Insights into Immunity and Aging

15 citations, November 2023 in “Immunity & ageing”

TLR4 is important in aging-related diseases and could be a new treatment target.

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community Seems I have acquired progressive kinking of the hair, potentially brought on by minox.

11 upvotes 7 years ago

User experienced hair kinking after starting minoxidil, despite being on finasteride for two years. Another user confirmed similar issues and suggested switching brands due to propylene glycol in minoxidil.

community Atherosclerosis as cause of balding and treatment

in Treatment 61 upvotes 1 year ago

Hair loss may be caused by calcification of capillaries in the scalp, restricting blood flow to hair follicles. A daily treatment regimen including high doses of Vitamins D and K, Magnesium, and Nattokinase could potentially decalcify these capillaries, improving blood flow and hair growth. However, some users warn against excessive Vitamin D intake and emphasize the need for medical consultation.

community 8 Month Update - Daily Topical Fin/Min, Weekly Microneedling, 40 y/o

in Progress Pictures 110 upvotes 1 year ago

User shared 8-month progress using daily topical Fin/Min, weekly microneedling, and supplements (biotin, zinc, saw palmetto, collagen). Others praised hairline regrowth and requested temple photos.

community Drinking minoxidil lands human in ICU with shock and heart failure

in Minoxidil 804 upvotes 2 months ago

A person mistakenly drank an entire bottle of topical minoxidil, leading to ICU admission with shock and heart failure. The incident highlights the dangers of ingesting topical treatments and the importance of proper usage and dosage.

community The story of RU58841/ PSK3841

in Research 622 upvotes 3 months ago

RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

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