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GlossaryAngiotensin-Converting Enzyme 2 (ACE-2)

regulates blood pressure and is a SARS-CoV-2 entry point

Angiotensin-Converting Enzyme 2 (ACE2) is a protein found on the surface of many cell types, including those in the lungs, heart, and kidneys. It plays a crucial role in regulating blood pressure by converting angiotensin II, a molecule that can increase blood pressure, into angiotensin 1-7, which has the opposite effect. ACE2 is also known for being the entry point for the SARS-CoV-2 virus, which causes COVID-19, making it a significant focus of medical research.

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Immunoreactivity of the SARS-CoV-2 Entry Proteins ACE-2 and TMPRSS-2 in Murine Models of Hormonal Manipulation, Aging, and Cardiac Injury

research Immunoreactivity of the SARS-CoV-2 Entry Proteins ACE-2 and TMPRSS-2 in Murine Models of Hormonal Manipulation, Aging, and Cardiac Injury

5 citations , December 2021 in “Scientific Reports”

Age affects how certain proteins involved in COVID-19 infection are expressed in mice, but sex hormones and heart injury do not.

research SARS-CoV-2 and Androgenic Alopecia: Exploring Links

January 2021 in “International Journal of Dermatology”

Possible link between COVID-19 and hair loss; more research needed.

research Alert to US Physicians: DHEA, Widely Used as an OTC Androgen Supplement, May Exacerbate COVID-19

7 citations , December 2020 in “Endocrine-related Cancer”

The over-the-counter supplement DHEA could make COVID-19 worse, especially in diabetics and people with G6PD deficiency.

research COVID-19 in Adult Patients With Pre-Existing Chronic Cardiac, Respiratory, and Metabolic Disease: A Critical Literature Review With Clinical Recommendations

122 citations , August 2020 in “Tropical Diseases Travel Medicine and Vaccines”

COVID-19 severely affects older adults with chronic heart, lung, or metabolic diseases.

research Repurposing Existing Drugs for COVID-19: An Endocrinology Perspective

34 citations , September 2020 in “BMC Endocrine Disorders”

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

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community 5 months until Europe, should I just shave it lol 24M

in Chat 9 upvotes 8 months ago

A 24-year-old experiencing hair thinning is using minoxidil, finasteride, and nutrafol, and plans to add keto shampoo and a derma roller to their routine. They are considering shaving their head before a trip to Europe and are advised to continue treatment, improve lifestyle habits, and possibly increase finasteride dosage for better results.

community After about 3 months of 2mg Estradiol (Sublingual) and 2.5mg Minox (Oral) daily

in Progress Pictures 160 upvotes 3 weeks ago

A person transitioning is using 2mg sublingual estradiol and 2.5mg oral minoxidil daily for hair regrowth, noting significant progress in three months. They plan to increase estrogen dosage and consider adding dutasteride, discussing the effects and challenges of transitioning.

community To all the young non-responders out there

in Update 120 upvotes 3 years ago

A 21 year old who has been taking various treatments for hair loss such as dutasteride, RU58841, minoxidil and finasteride with no results. Other users share their experiences of dealing with hair loss at an early age and offer advice on how to cope.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Coming up on ten months, I think it’s going alright!

in Progress Pictures 657 upvotes 5 months ago

The user has been using oral and topical minoxidil, finasteride, dermastamping, and multivitamins for hair loss, with plans to consider a hair transplant in the future. They are seeing gradual improvement and are content with the progress, preferring to stick with their current regimen rather than switching to other treatments like dutasteride.

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