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GlossaryAngiotensin-Converting Enzyme 2 (ACE-2)

regulates blood pressure and is a SARS-CoV-2 entry point

Angiotensin-Converting Enzyme 2 (ACE2) is a protein found on the surface of many cell types, including those in the lungs, heart, and kidneys. It plays a crucial role in regulating blood pressure by converting angiotensin II, a molecule that can increase blood pressure, into angiotensin 1-7, which has the opposite effect. ACE2 is also known for being the entry point for the SARS-CoV-2 virus, which causes COVID-19, making it a significant focus of medical research.

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Immunoreactivity of the SARS-CoV-2 Entry Proteins ACE-2 and TMPRSS-2 in Murine Models of Hormonal Manipulation, Aging, and Cardiac Injury

research Immunoreactivity of the SARS-CoV-2 Entry Proteins ACE-2 and TMPRSS-2 in Murine Models of Hormonal Manipulation, Aging, and Cardiac Injury

5 citations, December 2021 in “Scientific Reports”

Age affects how certain proteins involved in COVID-19 infection are expressed in mice, but sex hormones and heart injury do not.

research SARS-CoV-2 and Androgenic Alopecia: Exploring Links

January 2021 in “International Journal of Dermatology”

Possible link between COVID-19 and hair loss; more research needed.

research Alert to US Physicians: DHEA, Widely Used as an OTC Androgen Supplement, May Exacerbate COVID-19

7 citations, December 2020 in “Endocrine-related Cancer”

The over-the-counter supplement DHEA could make COVID-19 worse, especially in diabetics and people with G6PD deficiency.

research Repurposing Existing Drugs for COVID-19: An Endocrinology Perspective

34 citations, September 2020 in “BMC Endocrine Disorders”

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

research COVID-19: Understanding Inter-Individual Variability and Implications for Precision Medicine

58 citations, December 2020 in “Mayo Clinic Proceedings”

The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

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community 5 months until Europe, should I just shave it lol 24M

in Chat 9 upvotes 1 month ago

A 24-year-old experiencing hair thinning is using minoxidil, finasteride, and nutrafol, and plans to add keto shampoo and a derma roller to their routine. They are considering shaving their head before a trip to Europe and are advised to continue treatment, improve lifestyle habits, and possibly increase finasteride dosage for better results.

community To all the young non-responders out there

in Update 121 upvotes 2 years ago

A 21 year old who has been taking various treatments for hair loss such as dutasteride, RU58841, minoxidil and finasteride with no results. Other users share their experiences of dealing with hair loss at an early age and offer advice on how to cope.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 7 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Anything you use without scientific backing, just trusting your gut?

in Research/Science 13 upvotes 2 years ago

The conversation discusses using peppermint oil for hair loss, with one user applying it undiluted to the scalp and another combining it with finasteride and microneedling. Some believe in its effectiveness despite limited scientific evidence, and also mention rosemary oil as potentially beneficial.

community What should I expect from dutasteride?

in Finasteride/Dutasteride 2 upvotes 3 years ago

The user tried Minoxidil, PRP, Hair Carboxytherapy, and topical Dutasteride with limited success and is now on oral Dutasteride. They are experiencing some hair loss reduction but no significant density improvement, leading to feelings of depression.

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