4 citations
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January 2018 in “General Physiology and Biophysics” In this study, finasteride-treated WAG/Rij rats showed a significant increase in spike-wave discharges when administered endogenous steroids THPROG and THDOC, indicating potential exacerbation of absence seizures.
January 2017 in “Elsevier eBooks” This study suggests that progesterone may have a complex role in absence epilepsy, facilitating seizures through conversion to allopregnanolone, but potentially reducing them during pregnancy.
23 citations
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July 2003 in “Pharmacology, Biochemistry and Behavior” Finasteride blocks progesterone's effect on absence seizures in rats.
170 citations
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June 1974 in “BMJ” This study found that sodium valproate effectively stopped or reduced seizures in patients with various types of epilepsy, with best results in absence and myoclonic seizures, though it caused temporary hair loss in some cases.
73 citations
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January 1980 in “Annals of Neurology” This case report describes a child developing pancreatitis directly linked to valproic acid therapy.