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    Glossary Abiraterone

    inhibits androgen production to treat prostate cancer

    Abiraterone, also known as Zytiga, is a medication used primarily to treat prostate cancer. It works by inhibiting an enzyme called CYP17, which is involved in the production of androgens (male hormones) that can fuel the growth of prostate cancer cells. By reducing androgen levels, abiraterone helps to slow the progression of the disease.

    Research 10 of 82

    1. Abiraterone and spironolactone in prostate cancer: a combination to avoid Acta Clinica Belgica · 2018 · 9 citations
    2. Intratumoral <i>De Novo</i> Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors Cancer research · 2011 · 402 citations
    3. Revising the role of the androgen receptor in breast cancer Journal of Molecular Endocrinology · 2014 · 68 citations
    4. Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases The Journal of Steroid Biochemistry and Molecular Biology · 2013 · 51 citations
    5. Are sex discordant outcomes in COVID-19 related to sex hormones? Seminars in Oncology · 2020 · 42 citations
    6. Redefining hormone resistance in prostate cancer Therapeutic Advances in Medical Oncology · 2009 · 38 citations
    7. HSD3B1 Genotypes Conferring Adrenal-Restrictive and Adrenal-Permissive Phenotypes in Prostate Cancer and Beyond Endocrinology · 2019 · 30 citations
    8. Inhibition of 17α-hydroxylase/C17,20 lyase reduces gating deficits consequent to dopaminergic activation Psychoneuroendocrinology · 2013 · 19 citations
    9. Discovery of clinically approved drugs capable of inhibiting SARS-CoV-2 <i>in vitro</i> infection using a phenotypic screening strategy and network-analysis to predict their potential to treat covid-19 bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 13 citations
    10. Editorial: Androgen-dependent diseases and their treatment Frontiers in Endocrinology · 2024
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    Community 1

    1. Anyone know how to get second gen NSAA in the uk. Reddit · 21 Sept 2025

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