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GlossaryAbiraterone

inhibits androgen production to treat prostate cancer

Abiraterone, also known as Zytiga, is a medication used primarily to treat prostate cancer. It works by inhibiting an enzyme called CYP17, which is involved in the production of androgens (male hormones) that can fuel the growth of prostate cancer cells. By reducing androgen levels, abiraterone helps to slow the progression of the disease.

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research HSD3B1 Genotypes Conferring Adrenal-Restrictive and Adrenal-Permissive Phenotypes in Prostate Cancer and Beyond

30 citations , July 2019 in “Endocrinology”

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

research Management of Advanced Prostate Cancer Undergoing Major Shift

June 2011 in “Oncology times”

New treatments are making advanced prostate cancer management more complex but also more hopeful.

research Abiraterone and Spironolactone in Prostate Cancer: A Combination to Avoid

9 citations , November 2018 in “Acta Clinica Belgica”

Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.

Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors

research Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors

402 citations , August 2011 in “Cancer research”

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

research Redefining Hormone Resistance in Prostate Cancer

38 citations , December 2009 in “Therapeutic Advances in Medical Oncology”

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

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community Anyone know how to get second gen NSAA in the uk.

in Transgender 1 upvotes 5 months ago

A transwoman is struggling with hair loss despite using hormones, dutasteride, and Abiraterone, and is considering making her own treatments due to difficulty accessing them. She has also tried Eucapil and regularly uses Nizoral shampoo.

community Going to a cosmetic derm soon. What should I ask for?

in Female 3 upvotes 2 years ago

Female, 28, losing hair since 17, using 200mg Spiro. Tried Minoxidil and ketoconazole with limited success, considering oral minox and seeking alternative treatments from cosmetic dermatologist.

community Huge Group Buy is Now Live with New and Existing Treatments

in Product 146 upvotes 2 years ago

A group buy for hair loss treatments including Harmine 19a, TM5614, Abiraterone Acetate, and others. A compound, BMS-202, that can potentially reverse gray hair is also mentioned.

community New Treatments, and a Huge Group Buy with Lots of Research

in Research/Science 109 upvotes 2 years ago

A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

community My friend is so terrified of balding, he started microdosing estrogen…

in Treatment 1522 upvotes 3 months ago

A person is microdosing estrogen for hair loss after finasteride and dutasteride failed, risking feminizing effects. Alternatives like minoxidil, RU58841, or hair transplants are suggested.