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      learn Finasteride

      Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically
      • Finasteride for alopecia: the definitive guide to using it correctly. Finasteride 1 mg daily blocks DHT and, in trials, slowed hair loss in most men over 6 to 12 months, though some men do not respond and the benefit lasts only while the drug is taken. It is prescription-only, carries a pregnancy contraindication, and has reported sexual, mood, breast and semen side effects, some of which men report continuing after stopping.
      • Is Finasteride unbeatable or are there equally powerful alternatives? Finasteride has the longest record of trial evidence in male androgenetic alopecia; in pooled 24-week trials dutasteride increased hair counts more, and minoxidil, topical finasteride, PRP, LLLT and microneedling have supporting studies. Regulators warn that finasteride can cause sexual side effects, depression and suicidal thoughts that may persist after stopping, its label also lists breast, semen and other physical effects, and dutasteride now carries a precautionary mood warning; both are prescription-only, and dutasteride and oral minoxidil are off-label for hair loss.
      • Is finasteride safe? In one-year trials most men tolerated finasteride 1 mg, but its risks are not only sexual: US, UK and EU regulators warn of sexual dysfunction, depression and suicidal thoughts, and of sexual and mood symptoms that have continued after stopping, and men also report cognitive, anxiety and physical symptoms. How often lasting problems happen, and how much of that the drug causes, is not known; finasteride is prescription-only and must not be taken, or handled as crushed or broken tablets, by women who are or may be pregnant.
      • All 4 questions on Finasteride →

      learn Dutasteride

      5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride

      learn Minoxidil

      Vasodilator used on the scalp and, at low doses, as a tablet

    Research

    5 / 1000+ results

      research Clinical Case Notes. Propecia-associated bilateral cataract

      11 citations , February 2004 in “Clinical and Experimental Ophthalmology”
      In this case report, the authors suggest an association between prolonged finasteride use and anterior subcapsular cataracts, as observed in a 43-year-old man, marking the first reported instance.

      research Proscar and Propecia—A Therapeutic Perspective

      8 citations , July 2004 in “The Journal of Clinical Endocrinology & Metabolism”
      This article reviews the historical development of finasteride's approval for benign prostatic hyperplasia and discusses a trial that found decreased low-grade prostate cancer incidence but increased high-grade prostate cancer, with differing expert opinions on its use for cancer prevention.

      research Gynécomastie et finastéride (Propecia®) : 4 nouveaux cas

      3 citations , June 2004 in “Annales De Dermatologie Et De Venereologie”
      This review summarizes the adverse effects associated with 5α‐reductase inhibitors, noting slightly increased rates of decreased libido, erectile and ejaculatory dysfunction, gynecomastia, depression, and anxiety, with further studies needed to explore symptom prevalence and persistence.

      research Propecia may induce spermatogenic failure

      2 citations , September 2007 in “Fertility and Sterility”
      This study reported significant improvements in sperm concentration in two cases of azoospermia and severe oligospermia after discontinuing finasteride 1 mg used for hair loss.

    Community Join

    5 / 450 results

      community Propecia - Big Shed 3 Years In - Advice Sought

       4 upvotes 1 year ago
      A user experienced significant hair shedding after three years on finasteride, possibly due to stress or whey protein, and sought advice. Others suggested it might be a temporary shed, recommended monitoring for deficiencies, and mentioned adding dutasteride if needed.

      community Propecia/Finasteride Where does it come from?

       3 upvotes 4 years ago
      The user is taking finasteride 1mg from Blink pharmacy, sourced from Ascend Laboratories, with no noticeable side effects after 5 months. They also use Kirkland foam minoxidil, micro needling, and various supplements for hair treatment.