Search
for

    Did you mean 5-alpha-reductase inhibitor?
    Glossary 5-alpha-reductase inhibitor

    blocks enzyme converting testosterone to dihydrotestosterone (DHT)

    A 5-alpha-reductase inhibitor is a type of medication that blocks the enzyme 5-alpha-reductase, which is responsible for converting testosterone into dihydrotestosterone (DHT). By reducing DHT levels, these inhibitors can help treat conditions like male pattern baldness and benign prostatic hyperplasia (BPH).

    Related Terms

    Research 10 of 1000+

    1. Finasteride, a 5alpha-reductase inhibitor, blocks the anticonvulsant activity of progesterone in mice. PubMed · 1999 · 48 citations
    2. Treatment of male rats with finasteride, an inhibitor of 5alpha-reductase enzyme, induces long-lasting effects on depressive-like behavior, hippocampal neurogenesis, neuroinflammation and gut microbiota composition Psychoneuroendocrinology · 2018 · 37 citations
    3. <i>Curcuma aeruginosa</i>, a novel botanically derived 5α-reductase inhibitor in the treatment of male-pattern baldness: a multicenter, randomized, double-blind, placebo-controlled study Journal of Dermatological Treatment · 2011 · 34 citations
    4. Cloning, expression and characterization of rhesus macaque types 1 and 2 5alpha-Reductase: evidence for mechanism-Based inhibition by finasteride The Journal of Steroid Biochemistry and Molecular Biology · 1998 · 25 citations
    5. The new paradigm for androgenetic alopecia and plant-based folk remedies: 5α-reductase inhibition, reversal of secondary microinflammation and improving insulin resistance Journal of Ethnopharmacology · 2018 · 16 citations
    6. Health Promotion Potential of Vegetables Cultivated in Northern Thailand: A Preliminary Screening of Tannin and Flavonoid Contents, 5α-Reductase Inhibition, Astringent Activity, and Antioxidant Activities Journal of Evidence-Based Complementary & Alternative Medicine · 2017 · 10 citations
    7. Germination Enhances Phytochemical Profiles of Perilla Seeds and Promotes Hair Growth via 5α-Reductase Inhibition and Growth Factor Pathways Biology · 2025
    8. ANTIALOPECIA ACTIVITY EXPLORATION BY In-silico ANALYSIS OF BIOACTIVE COMPOUNDS FROM Sansevieria trifasciata PRAIN LEAVES THROUGH 5α-REDUCTASE INHIBITION 2023
    9. PROCESS VALIDATION OF BETA-SITOSTEROL HAIR GEL FORMULATION AND EVALUATION OF 5 ALPHA REDUCTASE INHIBITION IN VITRO FOR THE TREATMENT OF ANDROGENETIC ALOPECIA International Journal of Applied Pharmaceutics · 2023
    10. Overexpression of aldo-keto reductase 1C3 (AKR1C3) in LNCaP cells diverts androgen metabolism towards testosterone resulting in resistance to the 5α-reductase inhibitor finasteride The Journal of Steroid Biochemistry and Molecular Biology · 2012 · 45 citations
    All research results →

    Community 10 of 251

    1. Allopregnanolone deficiency by 5-ari inhibition (fin/dut users) Reddit · 11 Dec 2023
    2. BREAKTHROUGH: I’m a radiochemist and discovered a radioactive isotope scalp serum that OUTPERFORMS Minoxidil and 5-AR inhibitors! (Lab Data Inside) Reddit · 10 Jun 2025
    3. Why does this industry still revolve around 5-AR inhibitors? Reddit · 14 Jun 2021
    4. Did anybody use beta sisterol for hair loss? I saw in many articles in the internet that said that beta sisterol blocks dht by inhibiting 5a reductase type 2 enzyme and some reviews of people who said that it worked better than saw palmetto in terms of stoping hair loss and helping prostate. Reddit · 11 May 2023
    5. Similar 5ar inhibitors to fin? Reddit · 26 Jun 2021
    6. 4 months on oral dutasteride + one month and 3 weeks on topical minoxidil 5% Reddit · 23 May 2026
    7. Three months 0.5mg Dutasteride and 5% topical Minoxidil daily Reddit · 22 May 2026
    8. [Discussion] Trichoscopy in sudden-onset AGA: Pathology and reversibility of "Yellow Dots" without 5AR-inhibitors? Reddit · 22 Mar 2026
    9. Guys if you can’t take 5AR inhibitors still get on treatment ASAP Reddit · 6 Jan 2026
    10. Minoxidil is a 5ar inhibitor according to research Reddit · 4 Oct 2025
    All community results →

    Learn 5 of 6

    1. Dutasteride 5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride
    2. Finasteride Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically
    3. Saw Palmetto Palm-berry extract taken as a supplement
    4. Rosemary Herb whose oil is used in hair care
    5. Neem Oil Oil from the neem tree, used in traditional remedies
    All learn results →