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research Alopecia: unapproved treatments or indications

22 citations , March 2000 in “Clinics in Dermatology”

This study developed a method using HPLC with UV-DAD and ESI-MS detection to identify prohibited substances like minoxidil and hormones in cosmetic products advertised online for hair loss and skin conditions.

research The novel drug CS-891 inhibits 5alpha-reductase activity in freshly isolated dermal papilla of human hair follicles.

3 citations , December 2000 in “PubMed”

This study reports that the compound CS-891 can inhibit 5alpha-reductase activity in the dermal papillae of human hair follicles, suggesting potential for treating androgenetic alopecia.

research Improvement of Hair Loss by a Persimmon Leaf, Green Tea, and Sophora Fruit Extract Complex (BLH308)

2 citations , August 2022 in “Korean journal of medicinal crop science/Han-gug yagyong jagmul hag-hoeji”

This study investigated the antioxidant and anti-inflammatory effects of the plant extract BLH308 and its potential to reduce hair loss, showing significant antioxidant activity in vitro.

research Change in hair growth-related gene expression profile in human isolated hair follicles induced by 5-alpha reductase inhibitors – dutasteride and finasteride – in the presence of testosterone

1 citations , June 2021 in “Singapore Medical Journal”

This study suggests that type I 5-alpha reductase may also play a role in hair growth, with dutasteride potentially being more potent than finasteride in modulating key hair growth gene expressions.

Intraethnic Variation in Steroid-5-Alpha-Reductase Polymorphisms in Prostate Cancer Patients: A Potential Factor Implicated in 5-Alpha-Reductase Inhibitor Treatment

research Intraethnic variation in steroid-5-alpha-reductase polymorphisms in prostate cancer patients: a potential factor implicated in 5-alpha-reductase inhibitor treatment

4 citations , June 2015 in “Journal of Genetics/Journal of genetics”

This abstract reports funding sources for ongoing research and does not present any study results.

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Community Join

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community 18 Months Minoxidil 5% Before & After

in Progress Pictures 517 upvotes 1 year ago

The user used Minoxidil 5% for 18 months, seeing improved hair density but no change in the crown area. They are cautious about using Finasteride again due to past gynecomastia.

community Dutasteride might be better for your hairline. Some people have more type 1 5AR activity in their scalp than others.

in Finasteride/Dutasteride 52 upvotes 3 years ago

Dutasteride might be better for hairline due to varying levels of 5AR activity in scalps. Genetic tests can determine if finasteride is enough or if dutasteride is needed.

community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp

in Finasteride/Dutasteride 72 upvotes 3 years ago

Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.

community Why is the general consensus that if you can’t tolerate 5AR Inhibitors you’re “cooked”?

in Research/Science 15 upvotes 11 months ago

Alternatives to finasteride for hair loss include minoxidil, alfatrodial, fluridil, pyrilutamide, and Nizoral. These treatments may not be as effective as finasteride but can help slow hair loss progression.

community Am I seeing regrowth? (Halfway through month 5)

in Is this regrowth? 35 upvotes 1 year ago

The user is experiencing hair regrowth after five months on a treatment regimen including Musely's bloom+ pill (Minoxidil and Dutasteride), Nizoral, and microneedling. They are optimistic about the results and have not experienced any side effects.

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Learn

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learn Dutasteride

Heavy duty finasteride that comes with higher risks

learn Overview

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Clinics

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All 14 clinic results →

Experts

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