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    Did you mean 5-alpha-reductase deficiency?
    Glossary5α-reductase deficiency

    genetic condition impairing testosterone conversion to dihydrotestosterone (DHT)

    5α-reductase deficiency is a genetic condition where the body lacks sufficient levels of the enzyme 5α-reductase, which is crucial for converting testosterone into dihydrotestosterone (DHT). This deficiency can lead to atypical development of male genitalia in utero and can affect secondary sexual characteristics during puberty.

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      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia

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      a natural and far less effective alternative to Finasteride

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      community Trying to understand finasteride side effects and post finasteride syndrome

      in Finasteride/Dutasteride  70 upvotes 5 years ago
      The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

      community Dutasteride broked my liver (maybe)

      in Finasteride/Dutasteride  8 upvotes 3 years ago
      A user shared their experience with high cholesterol, glucose, and potential metabolic syndrome after using Finasteride and Dutasteride for hair loss. They plan to improve their health with diet and exercise before considering medication.

      community Hair loss causes are still a myth.

      in Chat  18 upvotes 4 years ago
      The conversation discusses the complexity of hair loss causes, suggesting that DHT sensitivity alone doesn't fully explain it. Treatments mentioned include finasteride and dutasteride.