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    Did you mean 5α-reductase activity?
    Glossary 5α-reductase activity

    enzyme converts testosterone into potent androgen dihydrotestosterone (DHT)

    5α-reductase activity refers to the function of the enzyme 5α-reductase, which converts testosterone into dihydrotestosterone (DHT), a more potent androgen. This process is significant in various biological functions, including the development of male characteristics and the regulation of hair growth. Elevated 5α-reductase activity is often associated with conditions like androgenetic alopecia (male pattern baldness) and benign prostatic hyperplasia.

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    1. Antioxidant and 5α-Reductase Inhibitory Activity of Momordica charantia Extract, and Development and Characterization of Microemulsion Applied sciences · 2022 · 1 citations
    2. Standardization of Amarantha hair oil with special reference to identification of β-sitosterol as major component having 5α-reductase inhibitory activity/hair growth promoting activity International Journal of Research in Dermatology · 2021
    3. Investigation of Antioxidant Activity of Cynanchi Wilfordii Radix and Inhibitory Effect of 5α-reductase mRNA in Human Dermal Papilla Cells Dong-ui saengni byeongni hakoeji · 2017
    4. Inhibitory activities of some traditional Chinese herbs against testosterone 5α-reductase and effects of Cacumen platycladi on hair re-growth in testosterone-treated mice Journal of Ethnopharmacology · 2015 · 25 citations
    5. Synthesis and activity of 8-substituted benzo[c]quinolizin-3-ones as dual inhibitors of human 5α-reductases 1 and 2 Bioorganic & Medicinal Chemistry Letters · 2004 · 9 citations
    6. Enzyme Inhibitory Activities of Marine Sponges Against Cholinesterase and 5α-Reductase 2019
    7. Synthesis and 5α-reductase inhibitory activity of 8-substituted benzo[ƒ]quinolinones derived from palladium mediated coupling reactions Bioorganic & Medicinal Chemistry Letters · 1998 · 14 citations
    8. Health Promotion Potential of Vegetables Cultivated in Northern Thailand: A Preliminary Screening of Tannin and Flavonoid Contents, 5α-Reductase Inhibition, Astringent Activity, and Antioxidant Activities Journal of Evidence-Based Complementary & Alternative Medicine · 2017 · 10 citations
    9. Phytochemicals With Anti 5-alpha-reductase Activity: A Prospective For Prostate Cancer Treatment F1000Research · 2021 · 8 citations
    10. Phytochemicals With Anti 5-alpha-reductase Activity: A Prospective For Prostate Cancer Treatment F1000Research · 2021 · 1 citations
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    Community 10 of 1000+

    1. Does caffeine inhibit 5-α-reductase? Reddit · 27 Dec 2019
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    3. PP405, a new hair growth stimulant that is completely different from minoxidil. Reddit · 29 Jun 2024
    4. Study shows further evidence that finasteride and dutasteride take 12-18 months or more to show significant results. Do NOT give up early Reddit · 25 Sept 2023
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    7. A warning to those using or thinking about using Dutasteride – Follow-up Reddit · 13 Mar 2021
    8. New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase Reddit · 22 May 2024
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    10. 5ar Type I in the frontal hair follicles - Dutasteride Reddit · 30 Apr 2024
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    Learn 3 of 24

    1. Neem Oil Oil from the neem tree, used in traditional remedies
    2. Dutasteride 5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride
    3. Finasteride Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically
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