4 citations
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July 2023 in “Experimental Dermatology” This study found that incorporating human adipose subcutaneous tissue in 3D organotypic skin cultures mimicking hypertrophic scar conditions improved epidermal homeostasis, formed a basement membrane similar to native skin, and reduced myofibroblast presence, indicating an anti-fibrotic effect.
3 citations
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April 2023 in “Cytotechnology”
January 2024 in “Biomaterials Research” This study found that human hair follicle dermal papilla cells cultivated as 3D spheroids in hexanoyl glycol chitosan-coated dishes formed hair-like structures, with minoxidil enhancing growth, and successfully integrated into artificial skin models, suggesting advancements for hair loss treatments and skin restoration therapies.
65 citations
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January 2021 in “Burns & Trauma” This study developed an in vitro model revealing that hair follicle spheroids enhanced both sweat gland and hair follicle differentiation within bioprinted scaffolds, while microenvironmental cues supported persistent regeneration.
48 citations
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March 2020 in “Stem Cell Research & Therapy” This study found that human adipose-derived stem cells co-cultured on a collagen sponge scaffold showed increased differentiation into keratinocytes, suggesting potential for improved skin wound healing.