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    Glossary3D Skin Models (3D Skin Constructs)

    laboratory-engineered tissues that mimic human skin structure

    3D Skin Models, also known as Three-Dimensional Skin Constructs or 3D Skin Equivalents, are laboratory-engineered tissues that mimic the structure and function of human skin. These models are created using layers of different cell types, such as keratinocytes and fibroblasts, to replicate the epidermis and dermis. They are used in research and testing to study skin biology, disease, and the effects of cosmetics or pharmaceuticals, providing a more accurate alternative to traditional 2D cell cultures and reducing the need for animal testing.

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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 5 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
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      community Am I taking out too much foam for a dose? Rogaine Minoxidil

      in Minoxidil 1 year ago
      This conversation discusses the topical application of Minoxidil, with various users providing advice on how to accurately measure a dose and keep it from melting too quickly. Others have shared their experiences using oral finasteride for hair loss treatments.

      community Scalp Micropigmentation while having hair

      in Treatment  6 upvotes 2 years ago
      User discusses scalp micropigmentation for denser hair appearance and its benefits compared to lifelong treatments. Special ink is used, which can fade and blur over time but can be topped up.

      community Surprisingly thorough study on He-Shou-Wu/Fo Ti

      in Research/Science  14 upvotes 1 year ago
      He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.