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research 5α-Reductase Type 2 Gene Variant Associations with Prostate Cancer Risk, Circulating Hormone Levels, and Androgenetic Alopecia

57 citations, February 2007 in “International Journal of Cancer”

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

research Finasteride in the Treatment of Hirsutism: New Therapeutic Perspectives

50 citations, July 1996 in “Fertility and Sterility”

Finasteride effectively treats hirsutism in women, but more research needed for long-term results.

research Serum 3α-Androstanediol-Glucuronide Is Decreased in Nonhirsute Women with Acne Vulgaris

10 citations, December 1996 in “Fertility and Sterility”

Women with acne have lower levels of a specific hormone marker than women without acne.

research Markers of Peripheral Androgen Action In Vivo and In Vitro

4 citations, October 1988 in “Clinics in Dermatology”

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

research Comparison of Finasteride Versus Flutamide in the Treatment of Hirsutism

75 citations, October 1999 in “European journal of endocrinology”

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

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community Bloodwork: what to test for?

in Finasteride/Dutasteride 7 upvotes 4 years ago

The user has been taking oral Finasteride and topical Essengen 6 Plus for hair loss and is experiencing increased depression. They plan to get bloodwork to check hormone levels and are seeking advice on which tests to include.

community Bile Acid-Mediated DHT Dysregulation Hypothesis

in Research/Science 13 upvotes 1 month ago

Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

community The theory that explains everything - First Evidence of Hair regrow attributed to upregulating 3aHSD

in Treatment 174 upvotes 3 years ago

Hair regrowth treatment involving 3aHSD enzyme shows 6% improvement in 18 weeks. Sulforaphane, L-Menthol, and Dexpanthenol are potential ingredients for new hair loss solution.

community Topical Finasteride reduced my DHT more than Oral Dutasteride

in Finasteride/Dutasteride 42 upvotes 2 years ago

Treatments for hair loss, including the experiences of topical finasteride and oral dutasteride. It also discusses Pyrilutamide, 0.025% topical concentration, Minoxidil, RU58841, and 1% finasteride gel dosage.

community Discussion: High DHT levels while on Fin+Dut with substantial progress (pics)

in Progress Pictures 63 upvotes 2 years ago

A user's experience with using 5AR inhibitors (Finasteride and Dutasteride) in combination with Minoxidil foam and microneedling, which resulted in substantial improvements to their crown density and hairline, despite high systemic levels of testosterone and dihydrotestosterone.

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