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Did you mean Androstanediol Glucuronide?

Glossary Androstanediol Glucuronide

metabolite of dihydrotestosterone linked to hair loss and hirsutism

Androstanediol Glucuronide (3α-Diol G) is a metabolite of dihydrotestosterone (DHT), a potent androgen hormone. It is often measured in clinical settings to assess androgen activity in the body, as elevated levels can be associated with conditions like androgenic alopecia (hair loss) and hirsutism (excessive hair growth).

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research Evidence of Increased 3‐Alpha‐Androstanediol Glucuronide in Female Pattern Alopecia: A Cross‐Sectional Observational Study Evaluating Ovarian, Adrenal, and Peripheral Androgens

May 2026 in “International Journal of Dermatology”

This study found that serum 3α-androstanediol glucuronide levels were higher in Indian women with female pattern hair loss and correlated with the severity of the condition.

research 3 alpha, 17 beta-androstanediol glucuronide in plasma. A marker of androgen action in idiopathic hirsutism.

179 citations , May 1982 in “The Journal of clinical investigation/The journal of clinical investigation”

This study found that plasma 3 alpha-diol glucuronide was markedly elevated in women with idiopathic hirsutism, suggesting it may be a marker of peripheral androgen action.

Female Androgenic Alopecia: The 3 Alpha, 17 Beta-Androstanediol Glucuronide/Sex Hormone Binding Globulin Ratio as a Possible Marker for Female Pattern Baldness

research Female androgenic alopecia. The 3 alpha,17 beta-androstanediol glucuronide/sex hormone binding globulin ratio as a possible marker for female pattern baldness

13 citations , September 1986 in “Archives of Dermatology”

This study found that women with female pattern baldness often had a higher ratio of 3 alpha,17 beta-androstanediol glucuronide to sex hormone-binding globulin and lower serum sex hormone-binding globulin, possibly indicating minimal androgen excess.

research Is 3α, 17β-androstanediol-glucuronide a diagnostic marker in women with androgenic manifestations?

3 citations , January 1992 in “Gynecological Endocrinology”

This study concluded that serum Adiol-G levels generally parallel testosterone levels and, therefore, do not effectively serve as a marker of peripheral androgen excess in women with androgenic symptoms.

research Correlation of Serum 3α-Androstanediol Glucuronide with Acne and Chest Hair Density in Men

51 citations , November 1988 in “The Journal of Clinical Endocrinology & Metabolism”

This study found that serum 3 alpha-Adiol-G levels in men are significantly associated with chest hair density and acne, indicating its role in reflecting androgen activity in peripheral tissues.

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community Has there been any update or progress on the 3-alpha hydroxysteroid dehydrogenase hypothesis?

13 upvotes 1 month ago

The conversation discusses the hypothesis that a lack of the enzyme 3-alpha hydroxysteroid dehydrogenase (3α-HSD) on the scalp may contribute to hair loss by allowing DHT to accumulate. Despite interest in this theory, no recent research has been conducted, and current treatments like finasteride and minoxidil remain the most supported options.

community Trying to understand finasteride side effects and post finasteride syndrome

70 upvotes 5 years ago

The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

community risks with finasteride and dutasteride

138 upvotes 1 year ago

Finasteride and dutasteride have potential risks, including post-finasteride syndrome, but are commonly used for hair loss. RU58841, minoxidil, and needling are suggested as alternatives, though all treatments carry risks.

community Finasteride and “anti-aging” effects

in Treatment 218 upvotes 1 year ago

Finasteride may help users look younger by suppressing DHT, affecting skin and hair. Users also emphasize skincare, sunscreen, and lifestyle for maintaining a youthful appearance.

community "but it will hurt my gains bro"

in Satire 1309 upvotes 1 year ago

The conversation humorously discusses hair loss treatments like Minoxidil, Finasteride, and Dutasteride, and their effects on hair and muscle gains. Users debate effectiveness and side effects, mixing scientific approaches with jokes.

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