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    Glossary3β-Hydroxysteroid Dehydrogenase

    enzyme crucial for converting steroid precursors into active hormones

    -Hydroxysteroid Dehydrogenase (-HSD) is an enzyme that plays a crucial role in the biosynthesis of all classes of hormonal steroids, including androgens, estrogens, and glucocorticoids. It catalyzes the conversion of Δ5--hydroxysteroids to Δ4-3-ketosteroids, a key step in the production of hormones that regulate various physiological processes, including hair growth and skin health.

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      community How I started reversing Male Pattern Baldness naturally ?

      in Question  7 upvotes 8 years ago
      The user reversed male pattern baldness using a pro-thyroid diet, lifestyle changes, and scalp stimulation exercises, without Minoxidil or Finasteride. They reported reduced dandruff, itchiness, oiliness, and experienced hair regrowth and thickening over 15 months.

      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 8 months ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community "but it will hurt my gains bro"

      in Satire  1309 upvotes 9 months ago
      The conversation humorously discusses hair loss treatments like Minoxidil, Finasteride, and Dutasteride, and their effects on hair and muscle gains. Users debate effectiveness and side effects, mixing scientific approaches with jokes.

      community The theory that explains everything. Please help me make this big!

      in Research/Science  2449 upvotes 4 years ago
      The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

      community GT20029 and PP405 the new fin and min that we been waiting for ?

      in Chat  31 upvotes 3 weeks ago
      PP405 and GT20029 are new hair loss treatments with different mechanisms from traditional options like Minoxidil and Finasteride. PP405 targets hair follicle stem cells to reactivate growth, while GT20029 works as an androgen receptor deleter, both requiring ongoing use for effectiveness.