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Research

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research Modulation of Murine Hair Follicle Function by Alterations in Ornithine Decarboxylase Activity

71 citations , May 1996 in “Journal of Investigative Dermatology”

This study found that overexpression of a mutated ornithine decarboxylase transgene in mice led to complete hair loss, which could be prevented or reversed with an ODC inhibitor.

research Role of Ornithine Decarboxylase in Human Hair Follicles

1 citations , January 2010

This study found that ornithine decarboxylase (ODC) may play a significant role in regulating human hair growth and hair cycle changes, as inhibiting ODC reduced follicular keratinocyte proliferation and human hair growth.

research Co-operation between follicular ornithine decarboxylase and v-Ha-ras induces spontaneous papillomas and malignant conversion in transgenic skin

88 citations , August 1998 in “Carcinogenesis”

This study found that overexpression of ornithine decarboxylase and activated Ha-ras together led to a high rate of tumor development in a mouse model without additional carcinogens.

research α‐Difluoromethylornithine, a polyamine inhibitor: its potential role in controlling hair growth and in cancer treatment and chemo‐prevention

9 citations , April 2006 in “International Journal of Dermatology”

This article reviews the potential for α-difluoromethylornithine to help control hair growth and prevent cancer, but it does not present new clinical results.

research Serendipity in Trichology

4 citations , January 2011 in “International Journal of Trichology”

Accidental findings have led to new hair treatment discoveries, like using blood pressure and diabetes medications for hair loss and unwanted hair.

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Community Join

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community 2 months of progress on topical minoxidil

6 upvotes 2 days ago

The conversation is about hair growth progress using topical minoxidil over two months, showing noticeable results without microneedling. The user shares their experience to encourage others considering the treatment.

community 2 years of Dut and Oral Min. Still room for improvement?

6 upvotes 3 days ago

The conversation discusses hair loss treatments, specifically using dutasteride, oral minoxidil, and considering RU58841 and microneedling for further improvement. The user is contemplating increasing the dutasteride dosage from 0.5mg to 2.5mg daily to enhance results.

community 2 months update: Topical Minoxidil

18 upvotes 1 week ago

The user experienced significant hair regrowth and density improvement using topical Minoxidil, Trioxidil shampoo, and Foligain supplements. They are considering adding finasteride to their treatment.

community 2 months on 1mg Fin and 3mg Minoxodil

11 upvotes 1 week ago

The user is experiencing new hair growth at the temples after 2 months of using 1mg finasteride and 3mg minoxidil. Others are optimistic about the progress and encourage patience.

community 2 year update: 1.2mg Fin, 3mg Min

1100 upvotes 1 week ago

The user experienced diffuse hair loss and successfully regrew thicker hair using 1.2mg Finasteride and 3mg Minoxidil over two years. They noticed significant progress around the six-month mark and used Hims for their medication.

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Learn

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learn 2-deoxy-D-Ribose

learn octapeptide-2

learn 1,2-Hexanediol

learn ceramide 2

learn Minoxidil

Minoxidil 2%, 5% and 10% which is better to use? In a randomized trial in men, 5% topical minoxidil produced more hair growth than 2%. There is no approved 10% product and no head-to-head trial showing it beats 5%; higher strengths mainly add irritation and systemic absorption. Approved strengths differ by sex, so check the label for your product.

learn Procyanidin B-2

learn Ketoconazole

Is there a difference between 1% and 2% ketoconazole? The documented differences are strength and supply: 1% ketoconazole shampoo is sold over the counter while 2% is usually prescription-only, and almost all of the trial evidence — including a 2015 Cochrane review — was gathered on the 2% shampoo rather than in a head-to-head comparison of the two strengths.

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