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research Cyproterone Acetate Quantification in Human Plasma by High-performance Liquid Chromatography Coupled to Atmospheric Pressure Photoionization Tandem Mass Spectrometry

1 citations , December 2011 in “Arzneimittelforschung”

This study developed a sensitive HPLC-MS/MS method for determining cyproterone acetate levels in human plasma and found no significant difference in its concentration between two oral formulations in bioequivalence testing.

research A comparative study of Aldactone® and Diane® in the treatment of hirsutism

20 citations , August 1987 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry”

This study suggests that Aldactone may be more effective than Diane in reducing hair growth, despite having minimal impact on hormone levels.

research Semen Parameters Among Transgender Women With a History of Hormonal Treatment

68 citations , February 2019 in “Urology”

Hormonal treatment in transgender women reduces semen quality, but stopping treatment may improve it.

research The Bis(1,2,3,4-tetrahydroisoquinoline) Alkaloids Cepharanthine and Berbamine Are Ligands of SK Channels

6 citations , January 2024 in “ACS Medicinal Chemistry Letters”

This study found that the alkaloids cepharanthine and berbamine bind to SK2 and SK3 channel subtypes with affinities that match their concentrations active against various diseases, prompting further investigation into SK channels' role in their therapeutic effects.

research Topical Finasteride: A Comprehensive Review of Androgenetic Alopecia Management for Men and Women

September 2023 in “Cureus”

This study reviewed early research on topical finasteride for androgenetic alopecia, finding it appears safe and promising, though further investigation is needed to determine optimal dosing, frequency, and potential applications for other types of alopecia.

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community 22M- 2 month progress on min fin and oral dut

in Progress Pictures 177 upvotes 1 year ago

A 22-year-old male shares his 2-month progress using a regimen of 0.5mg dutasteride daily, 1.5mm dermarolling weekly, a daily multivitamin, and a topical serum with 10% minoxidil and 0.1% finasteride. He reports impressive hair regrowth, especially at the hairline, and has experienced no sexual side effects.

community 10 days on 2.5 mg dut after 2.5 months on 0.5mg dut

7 upvotes 1 month ago

The conversation discusses the use of dutasteride for hair loss, with the original poster considering increasing their dose from 0.5mg to 2.5mg after 2.5 months, despite advice to wait at least a year to see results. Users advise against increasing the dose too quickly, suggesting that 0.5mg is effective and that higher doses offer minimal additional benefits while increasing the risk of side effects.

community Next month marks 2 years on Dutasteride. When does it start working?

in Finasteride/Dutasteride 36 upvotes 2 years ago

A user has been on dutasteride for nearly 2 years with no improvement in hair loss, expressing frustration. Other users suggest checking for other health conditions, getting bloodwork, and considering stopping TRT or trying finasteride.

community 5 alpha reductase type 1 is in brain tissue producing the main endogenous gabaergic allopregnanolone, not 2. How can finasteride as a 5ar2 lower that?

27 upvotes 1 year ago

Finasteride and dutasteride are discussed for hair loss, with concerns about their effects on neurosteroids and potential side effects like depression. Alternatives like topical estrogen and lifestyle changes are considered, with varying opinions on mental health and hair regrowth.

community What’s the highest minox % you home brewed ?

in Minoxidil 2 upvotes 2 years ago

A user discusses their experience with dissolving high concentrations of minoxidil in various ethanol/PG ratios and mentions difficulties with combining it with RU58841. They note that a 5% minoxidil solution remains stable, while higher concentrations tend to precipitate.

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learn Overview

learn Hair Transplant

What is the success rate of hair transplants? Hair transplants generally have a high success rate, but results can vary.

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