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research Unrevealing the Potential of Sansevieria trifasciata Prain Fraction for the Treatment of Androgenetic Alopecia by Inhibiting Androgen Receptors Based on LC-MS/MS Analysis, and In-Silico Studies

July 2022 in “Molecules”

This study identified seven new compounds from the plant Sansevieria trifasciata Prain and predicted that four of them may have better anti-alopecia activity than minoxidil through an in silico approach.

research Herbal nano-formulations for topical delivery

36 citations , September 2019 in “Journal of Herbal Medicine”

This review explores research on nanoformulations for enhancing the topical delivery of herbal medicines, noting potential benefits like improved bioavailability and sustained delivery, and emphasizes the need for safety and toxicity guidelines in developing these novel drug delivery systems.

research Protective Role of Nutritional Plants Containing Flavonoids in Hair Follicle Disruption: A Review

24 citations , January 2020 in “International Journal of Molecular Sciences”

This review discusses the potential benefits of flavonoid-containing botanicals, such as Panax ginseng, in reducing hair loss and promoting hair growth, but reports no new experimental results.

research Physiological and pharmacological features of the non-saponin components in Korean Red Ginseng

67 citations , February 2020 in “Journal of Ginseng Research”

This review evaluates and classifies the non-saponin components of Korean Red Ginseng, emphasizing their combined role with saponins in the plant's bioactivity, but reports no new clinical results.

research Structure optimization of tetrahydropyridoindole-based aldose reductase inhibitors improved their efficacy and selectivity

13 citations , October 2017 in “Bioorganic & Medicinal Chemistry”

This study found that compound 3, a tetrahydropyridoindole carboxymethylated at position 5, significantly inhibited sorbitol accumulation in both rat eye lenses and tissues affected by diabetes, indicating its potential as a lead compound for ALR2 inhibition.

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community Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men

26 upvotes 4 years ago

N-Acetyl-Cysteine (NAC) was found to improve hair parameters in men with early-onset androgenetic alopecia, showing increased terminal hair count and decreased vellus hair count, with good tolerability. NAC, used alone or with minoxidil, may help due to its antioxidant properties, though its effectiveness can vary among individuals.

community Short Peptides for Hair Loss: anyone tried any of these?

14 upvotes 5 months ago

Various peptides are discussed for treating male pattern baldness, with some available for topical use like GHK-Cu and Ac-KGHK, while others remain in research stages. Users are interested in experiences and sourcing these treatments.

community Fats on your Head to Stop Hair Loss?

140 upvotes 2 years ago

The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

community IGF-1 and Peptides? Miracle molecule waiting to be found

10 upvotes 1 year ago

The conversation discusses potential hair loss treatments focusing on stimulating IGF-1 at the follicle level using growth-factor cocktails and engineered peptides, such as Acetyl Tetrapeptide-3, Copper Tripeptide-1, Oligopeptide-20, Thymosin-β4, and Palmitoyl Tetrapeptide-7. It suggests that device-assisted delivery methods like microneedling may enhance effectiveness.

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