12 citations
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February 2020 in “The Journal of Clinical Endocrinology & Metabolism” This study found that a self-assessed modified Ferriman-Gallwey score of 10 or higher indicates excess body hair, and suggests androstenedione measurement should accompany testosterone when evaluating hyperandrogenism.
30 citations
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March 1980 in “European Journal of Endocrinology” This study suggests that genetic factors significantly influence adrenal androgen levels and the progression of puberty, with adrenal cortex maturation appearing independent of the hypothalamic-pituitary-gonadal axis.
This study found that nisoral treatment in patients with hyperandrogenism was associated with restored menstrual cycles and reduced pathological hair growth, along with decreased testosterone and increased estradiol and progesterone levels.
7 citations
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April 2019 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that 11α-hydroxyprogesterone is a potent inhibitor of 11βHSD2 in vitro and may serve as a precursor to unique C11α-hydroxy steroids in prostate cancer tissue.
4 citations
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August 2010 in “Acta Biologica Hungarica” This study found that novel compounds moderately inhibited 5α-reductase type 1 activity compared to finasteride, offering valuable data on structure-activity relationships.