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11α-Hydroxyprogesterone, a Potent 11β-Hydroxysteroid Dehydrogenase Inhibitor, Is Metabolized by Steroid-5α-Reductase and Cytochrome P450 17α-Hydroxylase/17,20-Lyase to Produce C11α-Derivatives of 21-Deoxycortisol and 11-Hydroxyandrostenedione In Vitro

research 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro

7 citations , April 2019 in “The Journal of Steroid Biochemistry and Molecular Biology”

This study found that 11α-hydroxyprogesterone is a potent inhibitor of 11βHSD2 in vitro and may serve as a precursor to unique C11α-hydroxy steroids in prostate cancer tissue.

research 11-Oxyandrogens in Adolescents With Polycystic Ovary Syndrome

9 citations , March 2022 in “Journal of the Endocrine Society”

This study found that testosterone more accurately predicts PCOS diagnosis than 11-oxyandrogens, which were linked with hirsutism severity and showed varying responses to contraceptive and metformin treatments.

research 11-oxyandrogen Concentrations in Adolescents With Polycystic Ovary Syndrome (PCOS)

May 2021 in “Journal of the Endocrine Society”

This study found that while 11-oxyandrogens do not aid in diagnosing PCOS, they correlate with hirsutism severity, and 11-ketotestosterone levels decrease with combined oral contraceptive therapy.

research 11 Treatment of hirsutism and acne with cyproterone acetate

43 citations , May 1986 in “Clinics in Endocrinology and Metabolism”

This review examines androgen status in male and female obesity and its influence on the metabolic syndrome, but reports no new clinical results.

research Endocrine treatment of benign prostatichypertrophy: Current concepts

11 citations , January 1991 in “Urology”

This article reviews the potential of combining antiandrogenic and antiestrogenic treatments for BPH, highlighting aromatase inhibitors, but presents no new clinical results; further research is needed.

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learn dehydroepiandrosterone

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community 11 months on topical minoxidil, and four months on topical finastride

11 upvotes 2 weeks ago

The conversation discusses hair loss treatments using topical minoxidil (5%) and topical finasteride, with no side effects reported. Users share application tips and express hope for regrowing hair, especially in the corners and temples.

community 11 months of progress on 1.25 fin only.

14 upvotes 1 month ago

The user experienced improved hairline results after 11 months on finasteride, with no significant side effects except temporary nipple sensitivity. They are considering adding minoxidil for better results but are waiting for full effects from finasteride.

community 11.5-month progress on Finasteride + Minoxidil (Topical → Oral). Looking for honest opinions on what’s still possible.

213 upvotes 2 months ago

OP experienced significant hair regrowth using 1 mg oral Finasteride and switched from topical to 2.5 mg oral Minoxidil, with concerns about miniaturized hairs near the hairline. OP plans to grow out their hair and is curious about future regrowth potential and hairstyle suitability.

community 11 months on oral .25 min and .5 dut

164 upvotes 3 months ago

The user switched from finasteride to dutasteride and experienced hair regrowth with no side effects, using 2.5mg oral minoxidil and 0.5mg dutasteride. The user noticed improved mood due to more hair and found the treatment effective, starting at age 21.

community 11 months progress what do we think

in Is this regrowth? 23 upvotes 5 months ago

The user shared 11 months of progress using oral finasteride and minoxidil for hair regrowth, reporting no side effects. Feedback from others noted improved hair thickness and health.

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Salon 11/18 Hair & Makeup StudioJacksonville, FL · US

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