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research Use of rotary echoes in 2H magic-angle spinning NMR for the quantitative study of molecular dynamics

15 citations , May 2009 in “Chemical Physics Letters”

This study demonstrated that a metric based on rotational echo intensity in 2H magic-angle spinning NMR can derive kinetic information for conformational exchange without complex modelling, achieving activation barriers consistent with prior findings.

research Validated RP-TLC Method with Densitometry for Assay of Finasteride in Simple Pharmaceutical Dosage Form

2 citations , April 2018 in “Current Pharmaceutical Analysis”

This study developed a new, simple, and economical RP-TLC method with densitometry that is suitable for routine analysis of finasteride in tablet dosage form, meeting analytical validation criteria.

Synthesis and In Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-Oxo-4-Androstene-17β-Carboxamides as 5α-Reductase Inhibitors and Antiandrogens

research Synthesis and in Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-oxo-4-androstene-17.beta.-carboxamides as 5.alpha.-Reductase Inhibitors and Antiandrogens

12 citations , April 1995 in “Journal of Medicinal Chemistry”

In this study, 4-substituted N-(1,1-dimethylethyl)-3-oxo-4-androstene-17.beta.-carboxamides were synthesized and evaluated in vitro as potential 5 alpha-reductase inhibitors and antiandrogens.

research Synthesis and 5α-Reductase Inhibitory Activity of C21 Steroids Having 1,4-diene or 4,6-diene 20-ones and 4-Azasteroid 20-Oximes

186 citations , December 2011 in “Molecules”

This study reported that while no synthesized compounds surpassed finasteride in 5α-reductase inhibitory activity, certain 4-azasteroid-2-oximes exhibited notable inhibition.

research 2-Substituted 4-(Thio)chromenone 6-O-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase

111 citations , August 2002 in “Journal of Medicinal Chemistry”

This study reports that 2-(1-Adamantyl)-4H-thiochromen-4-on-6-O-sulfamate is the most potent steroid sulfatase inhibitor identified so far, exhibiting 170-fold higher activity than the lead compound estrone sulfamate.

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community 1.4 years on finasteride, only lately have signs of improvement been showing

in Progress Pictures 232 upvotes 1 year ago

The user noticed hair density improvement after 1.4 years on finasteride, with additional use of minoxidil on the temples. Other users discussed various treatments like dutasteride, estrogen, and hair transplants, sharing personal experiences and advice.

community 14 months fin, losing ground and hope.

52 upvotes 3 weeks ago

A 22-year-old is experiencing hair loss despite using 0.8mg oral finasteride for 14 months and 5% topical minoxidil consistently for 6 months. Suggestions include switching to dutasteride, trying oral minoxidil, using ketoconazole shampoo, and consulting a dermatologist for scalp inflammation.

community 14 month progress update - 4 in 1 topical solution (sorry for the low quality before)

59 upvotes 1 month ago

The user shared a 14-month progress update using a 4-in-1 topical solution containing 0.3% finasteride, 7% minoxidil, 2.2% ketoconazole, and 0.2% biotin, applied nightly. They reported good results without microneedling and prefer the topical form over oral medication.

community 14 month progress on Oral Min/dutasteride

32 upvotes 1 month ago

The user shared 14-month progress using oral minoxidil and dutasteride, noting healthier hair corners after switching from finasteride. They plan a future hair transplant for a lower hairline.

community 14 months - 1mg fin & 5% topical minoxidil results

in Progress Pictures 452 upvotes 4 months ago

Significant hair regrowth was achieved using 1mg finasteride and 5% topical minoxidil over 14 months, with only initial shedding and mild scalp irritation as side effects. Consistency and early treatment are recommended for optimal results.

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learn Hair Transplant

What results can I expect from a hair transplant? Expect new hair growth in 3-4 months, with full results in 9-12 months.
How long does a hair transplant procedure take? A hair transplant procedure typically takes 4 to 8 hours.
How much do 2000 hair grafts cost? The cost for 2000 hair grafts typically ranges from $500 to $12,800.
All 4 questions on Hair Transplant →

learn Scalp Micropigmentation

How long does Scalp Micropigmentation last, and does it need touch-ups over time? Scalp micropigmentation lasts 2 to 8 years and requires touch-ups every 1 to 5 years.

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Dixant Chhikara, MBBS

Dionne Molden

Diane Bosch

Diane Bowe

Diane Giannotto

Dianelsie, Registered Nurse