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research VITAMIN D RESISTANT RICKETS WITH ALOPECIA: A FORM OF END ORGAN RESISTANCE TO 1,25 DIHYDROXY VITAMIN D

82 citations , April 1981 in “Clinical endocrinology”

This study describes a case of vitamin D resistant rickets in a young girl due to end organ unresponsiveness, highlighting a possible new subtype of the disorder with distinct clinical features.

research Hereditary 1,25‐Dihydroxyvitamin D‐Resistant Rickets in a Pomeranian Dog Caused by a Novel Mutation in the Vitamin D Receptor Gene

30 citations , October 2009 in “Journal of Veterinary Internal Medicine”

This report describes a unique case of hereditary vitamin D-resistant rickets (HVDRR) in a dog, caused by a VDR gene mutation resulting in severe hypocalcemia and bone issues, which presented with symptoms similar to those observed in humans.

Pharmacokinetic Parameters and Mechanisms of Inhibition of Rat Type 1 and 2 Steroid 5α-Reductases: Determinants for Different In Vivo Activities of GI198745 and Finasteride in the Rat

research Pharmacokinetic parameters and mechanisms of inhibition of rat type 1 and 2 steroid 5α-reductases: determinants for different in vivo activities of GI198745 and finasteride in the rat 3 3Abbreviations: r5AR1, rat 5α-reductase 1; r5AR2, rat 5α-reductase 2; and DHT, dihydrotestosterone.

22 citations , October 2001 in “Biochemical Pharmacology”

This study found that GI198745 acts as a time-dependent inhibitor of rat 5α-reductase type 2 but a rapid-equilibrium inhibitor of type 1, potentially making it more effective than finasteride in preventing rat prostate growth.

Bicalutamide 25 Mg Associated With Minoxidil 1 Mg Versus Minoxidil 1 Mg for Female-Pattern Hair Loss: A Randomized Double-Blind Clinical Trial

research Bicalutamide 25 mg associated with minoxidil 1 mg versus minoxidil 1 mg for female-pattern hair loss: A randomized double-blind clinical trial

January 2025 in “JAAD International”

This randomized, controlled clinical trial found that combining 25 mg/d bicalutamide with 1 mg/d minoxidil for 24 weeks did not enhance hair density improvement in female pattern hair loss compared to 1 mg/d minoxidil alone, with no significant difference observed between the groups.

Synthesis of Spiro[cyclohexane-1,2'-[2H]indene] Derivatives as Inhibitors of Steroid 5α-Reductase

research Synthesis of Spiro[cyclohexane-1,2?-[2H]indene] derivatives as inhibitors of steroid 5?-reductase

8 citations , June 1995 in “Helvetica Chimica Acta”

This article outlines the synthesis of spiro[cyclohexane‐1,2′‐[2 H ]indene] derivatives similar to known steroid 5α‐reductase inhibitors, but it does not report experimental findings.

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community 1.25mg oral minoxidil every day, 0.5mg dutasteride every other day - 4 months progress

74 upvotes 1 month ago

OP is using 1.25mg oral minoxidil daily and 0.5mg dutasteride every other day for hair loss, with noticeable progress after 4 months and no significant side effects. OP experienced chest pain with a higher dose of minoxidil previously but has had no issues with the current regimen.

community 1.25mg oral minoxidil effectiveness

in Minoxidil 6 upvotes 5 months ago

The conversation discusses the effectiveness and side effects of taking 1.25mg oral minoxidil for hair loss, with some users suggesting starting at a lower dose to minimize side effects before potentially increasing to 2.5mg. Concerns about cardiovascular side effects and the importance of individual responses to dosage are highlighted.

community 1.25mg Finasteride (6times a week)

3 upvotes 7 months ago

A 25-year-old is using 1.25mg finasteride six times a week and 5% topical minoxidil daily for hair loss. They are experiencing reduced libido and erectile issues, possibly due to stress, and are questioning if the finasteride dosage is affecting DHT suppression.

community 1.25mg oral minoxidil-3 month progress

in Progress Pictures 633 upvotes 1 year ago

A 44-year-old man experienced significant hair regrowth after switching from topical to 1.25mg oral minoxidil and 0.5mg daily finasteride, with no side effects. He noticed hair thickening after two months and credits the oral form's effectiveness.

community 21M 2.5 min 1 fin oral , 2.5 years

in Progress Pictures 6 upvotes 1 month ago

A 21-year-old male has been using 2.5 mg oral minoxidil and 1 mg finasteride for 2.5 years to address hair loss, with no side effects but experiencing mild shedding. Users suggest considering dutasteride and increasing minoxidil dosage for better results.

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learn Overview

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learn Ketoconazole

Is there a difference between 1% and 2% ketoconazole? The documented differences are strength and supply: 1% ketoconazole shampoo is sold over the counter while 2% is usually prescription-only, and almost all of the trial evidence — including a 2015 Cochrane review — was gathered on the 2% shampoo rather than in a head-to-head comparison of the two strengths.

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How long does Scalp Micropigmentation last, and does it need touch-ups over time? Scalp micropigmentation lasts 2 to 8 years and requires touch-ups every 1 to 5 years.

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How many grafts do I need for a hair transplant? You typically need 1,000 to 7,000 grafts depending on hair loss extent and goals.
How much do 2000 hair grafts cost? The cost for 2000 hair grafts typically ranges from $500 to $12,800.
What results can I expect from a hair transplant? Expect new hair growth in 3-4 months, with full results in 9-12 months.

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