Fabrication of Polyvinyl Pyrrolidone-K90/Eudragit RL100-Based Dissolving Microneedle Patches Loaded with Alpha-Arbutin and Resveratrol for Skin Depigmentation

    January 2023 in “ Biomaterials Science ”
    Nway Nway Aung, Supusson Pengnam, Tanasait Ngawhirunpat … Boonnada Pamornpathomkul
    Studysummary This study investigated the use of dissolving microneedle patches to improve the skin-lightening effects of alpha-arbutin and resveratrol, finding that the patches enhanced intradermal delivery and slightly decreased the melanin index without affecting skin hydration or causing irritation over 24 hours.
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