Procedural Promotion of Wound Healing by Graphene-Barium Titanate Nanosystem with White Light Irradiation
August 2023
in “
International Journal of Nanomedicine
”
TLDR A new wound healing treatment using a graphene-based material with white light speeds up healing and reduces infection and scarring.
The study investigated a novel Graphene-Barium Titanate (GBT) nanosystem for wound healing. The GBT nanosystem, when exposed to white light, generates reactive oxygen species (ROS) that effectively kill E. coli and S. aureus bacteria, preventing wound infection. Additionally, the graphene component of the system acts as a scaffold to accelerate fibroblast proliferation and migration to the wound, promoting wound healing. In vivo tests on mice showed that GBT, combined with white light, significantly accelerated wound healing, reduced inflammation, and promoted tissue regeneration and collagen deposition within 8 days, with minimal scar formation. The study also confirmed the biosafety of GBT, as it did not cause significant damage to major organs.
