Implication of VEGF, Steroid Hormones and Neuropeptides in Hair Follicle Cell Responses

This review from 2002 explored the regulation of hair follicle cell responses, focusing on the roles of VEGF, steroid hormones, and neuropeptides. It highlighted the independent progression of hair follicles through growth phases and the presence of multi-potent stem cells. The study identified messenger molecules and pathways involved in hair growth and cycling, noting that only a few signals were well understood. The research demonstrated changes in receptor expression patterns in dermal papilla cells and the interaction between hormonal, vascular, and neuropeptide components. The conclusion suggested that a combination of these factors was necessary for regulating hair growth, offering potential insights for developing new treatments for hair loss.