TLDR Vogt-Koyanagi syndrome often leads to partial or complete blindness and responds poorly to treatment.
Vogt-Koyanagi syndrome is a recognized clinical condition characterized by severe bilateral uveitis, poliosis, vitiligo, alopecia, and dysacousia. The disease has a prolonged course, responds poorly to treatment, and often results in partial or complete blindness. First reported by Vogt in 1906 and later detailed by Koyanagi in 1929, the syndrome involves spontaneous uveitis with associated hair and skin depigmentation, hair loss, and hearing disturbances.
17 citations,
July 1994 in “Journal of Dermatological Science” The cause of alopecia areata is likely a mix of genetics, immune system issues, and environmental factors, with more research needed to understand it fully.
89 citations,
October 1996 in “Dermatologic Clinics” Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.
11 citations,
May 2011 in “The Journal of Dermatology” A man had two rare autoimmune diseases that might be connected.
May 2011 in “Journal of Clinical Neuroscience” The woman was diagnosed with Vogt–Koyanagi–Harada disease and successfully treated with medication, restoring her vision and stopping headaches.
532 citations,
August 2011 in “Journal of the American Academy of Dermatology” Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.
