Use of H-1 Antihistamine in Dermatology: More Than Itch and Urticaria Control: A Systematic Review

    April 2021 in “ Dermatology and Therapy ”
    Chang‐Yu Hsieh, Tsen‐Fang Tsai
    Studysummary This review identifies several off-label uses of H-1 antihistamines in dermatology beyond itch and urticaria control, though the evidence is weak and further trials are needed.
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    Research cited in this study 8

    1. Efficacy of Antihistamines in Combination with Topical Corticosteroid and Superficial Cryotherapy for Treatment of Alopecia Areata: A Retrospective Cohort Study Journal of the American Academy of Dermatology · 2020
    2. Frontal Fibrosing Alopecia: An Update on the Hypothesis of Pathogenesis and Treatment International Journal of Women's Dermatology · 2019
    3. Lichen Planopilaris in a Latin American (Chilean) Population: Demographics, Clinical Profile, and Treatment Experience Clinical and experimental dermatology · 2017
    4. A Preliminary Study on Topical Cetirizine in the Therapeutic Management of Androgenetic Alopecia Journal of Dermatological Treatment · 2017
    5. Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia Science Translational Medicine · 2012
    6. Therapeutic Hotline: Effectiveness of the Association of Cetirizine and Topical Steroids in Lichen Planus Pilaris - An Open-Label Clinical Trial Dermatologic therapy · 2010
    7. Experimental Evaluation of Ebastine, a Second-Generation Antihistamine, as a Supportive Medication for Alopecia Areata Journal of Dermatological Science · 2010
    8. Scalp Dysesthesia: A Study on Chronic Pain and Itchiness Archives of Dermatology · 1998